Document Detail

Pancreatic necrosis: an early finding in severe acute pancreatitis.
MedLine Citation:
PMID:  8483878     Owner:  NLM     Status:  MEDLINE    
Despite the clinical importance of pancreatic necrosis in the course of acute pancreatitis, little is known about when it develops. Serum C-reactive protein (CRP) is a reliable parameter with a high deduction rate for pancreatic necrosis. We analyzed 199 patients with acute pancreatitis. The development of pancreatic necrosis was ascertained by a daily measurement of serum CRP in 45 patients with contrast-enhanced computed tomographic-proven necrotizing pancreatitis. In all 45 cases, the criteria for pancreatic necrosis were satisfied within the first 4 days of the onset of symptoms. This indicates that pancreatic necrosis is an early finding that develops within hours.
R Isenmann; M Büchler; W Uhl; P Malfertheiner; M Martini; H G Beger
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pancreas     Volume:  8     ISSN:  0885-3177     ISO Abbreviation:  Pancreas     Publication Date:  1993 May 
Date Detail:
Created Date:  1993-06-02     Completed Date:  1993-06-02     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8608542     Medline TA:  Pancreas     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  358-61     Citation Subset:  IM    
Department of Surgery, University of Ulm, Germany.
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MeSH Terms
Acute Disease
Aged, 80 and over
C-Reactive Protein / analysis
Middle Aged
Pancreas / pathology*,  radiography
Pancreatitis / pathology*
Prospective Studies
Tomography, X-Ray Computed
Reg. No./Substance:
9007-41-4/C-Reactive Protein

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