Document Detail


Pancreatic microcirculation in the monkey with special reference to the blood drainage system of Langerhans islets: light and scanning electron microscopic study.
MedLine Citation:
PMID:  8838272     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The microcirculation of the pancreas in 20 monkeys (Macaca mulatta) was further studied by scanning electron microscopy (SEM) of vascular corrosion casts and light microscopy (LM) of Chinese ink-injected/cleared tissues. The results revealed that 91% of islets observed received arterial blood from the terminal branches of the intralobular arteries--the afferent arterioles, and 9% received no arterial blood, being entirely supplied by the efferent vessels of the intermediate or large islets. Some islets received blood from the translobular afferent arterioles of the adjacent lobule. Two patterns of islet drainage channels with different features in the monkey were demonstrated in our study. These patterns might be termed as continuous or convergent portal vessels. All islets possessed continuous portal vessels, 7-8 microns in diameter, which ran a short distance (approximately 100 microns) and then drained into the peri-islet acinar region, forming a typical continuous insulo-acinar portal system. About 21% of the islets possessed one or two convergent portal vessels, occasionally more. This was first observed in the monkey. These vessels were relatively long and/or thick and drained into different regions: (1) the acinar region far from the islet in the lobule, forming a convergent insulo-acinar portal system, (2) crossed the interlobular septum into an adjacent lobule where sometimes no islet existed and then drained into the exocrine acinar region, forming a translobar convergent insulo-acinar portal system, (3) drained into an adjacent small islet through the insulo-insular drainage vessels--one part of the drainage system of the islets. Translobular vascular anastomoses observed between the microcirculation of pancreatic lobules in the monkey formed a new arrangement of pancreatic microcirculation-translobular pancreatic microcirculation. The functional and clinical significance of the pancreatic portal circulation and translobular circulation is discussed in this report.
Authors:
Z G Zhou; X H Gao; W U Wayand; L J Xiao; Y Du
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical anatomy (New York, N.Y.)     Volume:  9     ISSN:  0897-3806     ISO Abbreviation:  Clin Anat     Publication Date:  1996  
Date Detail:
Created Date:  1996-12-11     Completed Date:  1996-12-11     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  8809128     Medline TA:  Clin Anat     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1-9     Citation Subset:  IM    
Affiliation:
Second Department of Surgery, General Hospital of Linz, Austria.
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MeSH Terms
Descriptor/Qualifier:
Animals
Arterioles / anatomy & histology
Corrosion Casting
Female
Islets of Langerhans / blood supply*,  ultrastructure
Macaca mulatta
Male
Microcirculation*
Microscopy, Electron
Microscopy, Electron, Scanning
Models, Biological
Pancreas / blood supply*,  cytology
Reference Values

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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