Document Detail


Pancreatic insulin response in relation to exercise training.
MedLine Citation:
PMID:  6357415     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The present study was undertaken to measure the effects of exercise training on pancreatic insulin secretion in response to glucose and nonglucose stimuli. Wistar female rats with an initial body weight of approximately 180 g were divided into trained and sedentary groups. After a period of 10 weeks of training, glucose-, tolbutamide-, and arginine-tolerance tests were performed in vivo in both trained and untrained animals. The tests were done in nonanesthetized animals 40 h after the last exercise bout. It was found that exercise training leads to a diminution of plasma insulin levels after either glucose, tolbutamide, or arginine administration. These results present direct evidence that exercise training reduces plasma insulin response not only to glucose but also to nonglucidic secretagogues.
Authors:
D Richard; J LeBlanc
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Canadian journal of physiology and pharmacology     Volume:  61     ISSN:  0008-4212     ISO Abbreviation:  Can. J. Physiol. Pharmacol.     Publication Date:  1983 Oct 
Date Detail:
Created Date:  1984-01-27     Completed Date:  1984-01-27     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0372712     Medline TA:  Can J Physiol Pharmacol     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  1194-7     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Arginine / pharmacology
Female
Insulin / secretion*
Islets of Langerhans / secretion*
Physical Exertion*
Rats
Secretory Rate / drug effects
Tolbutamide / pharmacology
Chemical
Reg. No./Substance:
11061-68-0/Insulin; 64-77-7/Tolbutamide; 74-79-3/Arginine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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