Document Detail


Pancreatic duct pressure in chronic pancreatitis.
MedLine Citation:
PMID:  7114368     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The wide variety of surgical procedures available for the relief of pain in patients with chronic pancreatitis attests to a lack of understanding of the precise mechanisms responsible for the onset of pain in this condition. In the development of surgical procedures designed to "decompress" the pancreatic duct in chronic pancreatitis, it has been tacitly assumed that pancreatic duct hypertension exists and is important in the pathophysiology of the disease. In 19 patients with chronic pancreatitis and dilated pancreatic ducts, pancreatic duct pressure was significantly higher than in control patients. In view of the dramatic relief of preoperative pain after procedures for decompressing the pancreatic ducts, ductal hypertension has been confirmed as an important mechanism of pain production in this group of patients.
Authors:
E L Bradley
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of surgery     Volume:  144     ISSN:  0002-9610     ISO Abbreviation:  Am. J. Surg.     Publication Date:  1982 Sep 
Date Detail:
Created Date:  1982-10-21     Completed Date:  1982-10-21     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370473     Medline TA:  Am J Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  313-6     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Chronic Disease
Female
Humans
Male
Manometry
Pancreatic Ducts / physiopathology*
Pancreatic Pseudocyst / physiopathology
Pancreatitis / physiopathology*
Pressure

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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