| Pancreatic dual-source dual-energy CT: Is it time to discard unenhanced imaging? | |
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MedLine Citation:
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PMID: 22094183 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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AIM: To compare pancreatic virtual unenhanced (VUE) and true unenhanced (TUE) images and to calculate the potential dose reduction by omitting the conventional unenhanced scan. MATERIALS AND METHODS: Fifty-one patients with known or suspected pancreatic masses underwent contrast-enhanced computed-tomography (CT) during unenhanced and portal venous phases acquired in single-energy (SE) mode, and pancreatic parenchymal phase acquired in dual-energy (DE) mode. The image quality (IQ) and image noise (IN) of TUE and VUE images were evaluated. The effective dose of a combined DE/SE dual-phase protocol was compared with that of a theoretical standard SE triple-phase protocol. The results were tested for statistical significance using the Cohen's k, the Wilcoxon's signed rank test, and the paired t-test; p-values of less than 0.05 were considered significant. RESULTS: Mean TUE and VUE IQ were 1.5 ± 0.6 and 1.6 ± 0.6 (k = 0.891), with no significant difference (p > 0.05). Mean TUE and VUE IN were 12.3 ± 1.6 and 10.3 ± 1.5 HU, and resulted significantly different (p < 0.001). Mean effective doses for a combined DE/SE dual-phase protocol and SE triple-phase protocol were 8.9 ± 2.4 mSv (range 4.8-16.2 mSv) and 12.1 ± 3.1 mSv (range 6.4-21.1 mSv). The calculated mean dose reduction achievable by omitting the unenhanced scan was 26.7 ± 9.7% (range 10-46.1; p < 0.001). CONCLUSION: VUE images are feasible for pancreatic abdominal CT. A combined DE/SE dual-phase protocol permits a significant reduction in dose exposure to patients. |
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Authors:
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Achille Mileto; Silvio Mazziotti; Michele Gaeta; Antonio Bottari; Fabrizio Zimbaro; Claudio Giardina; Giorgio Ascenti |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-11-15 |
Journal Detail:
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Title: Clinical radiology Volume: - ISSN: 1365-229X ISO Abbreviation: - Publication Date: 2011 Nov |
Date Detail:
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Created Date: 2011-11-18 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 1306016 Medline TA: Clin Radiol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved. |
Affiliation:
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Department of Radiological Sciences, Policlinico "G. Martino", Messina, Italy. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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