Document Detail


PANCREATIC DISEASE IN INFANCY AND CHILDHOOD. SURGICAL IMPLICATIONS.
MedLine Citation:
PMID:  14254965     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Surgeons whose practice involves many infants and children should be acquainted with all abnormalities of pancreatic malformation and function. Conditions amenable to surgical treatment are few, but serious. Trauma to the pancreas in childhood is most commonly diagnosed by fever, leukocytosis, rectus spasm and elevated serum amylase. Drainage of the lesser sac and debridement of devitalized tissue may prevent the sequelae of pseudocyst formation which seems to follow the untreated injury. True congenital cysts are characterized by an epithelial lining.Mucoviscidosis complicated by meconium ileus remains a challenging disease of the newborn that requires early operation. Ten per cent of infants with cystic fibrosis may be threatened by intestinal obstruction from this cause. Some children surviving the newborn period go on to develop obstruction later. Annular malformation of pancreas may produce upper intestinal (duodenal) obstructive symptoms immediately after birth. Surgical correction by duodenojejunostomy should be postponed only long enough to correct severe fluid or electrolyte imbalances. Idiopathic spontaneous hypoglycemia has the most serious prognosis if convulsions are allowed to recur. Increased metabolic rates in infants increase the need for control of blood sugar levels by either administration of cortisone or pancreatic resection. If adenoma is the cause, a conservative resection of the tumor suffices. If serial frozen section fails to reveal either tumor or hypertophy of insulin-producing cells, blind pancreatectomy may be indicated, for irreversible brain damage develops early in uncontrolled hypoglycemia.
Authors:
R H WHITTLESEY
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  California medicine     Volume:  102     ISSN:  0008-1264     ISO Abbreviation:  Calif Med     Publication Date:  1965 Feb 
Date Detail:
Created Date:  1965-05-01     Completed Date:  1996-12-01     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0410260     Medline TA:  Calif Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  110-5     Citation Subset:  OM    
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MeSH Terms
Descriptor/Qualifier:
Child*
Congenital Abnormalities*
Cystic Fibrosis*
Hypoglycemia*
Infant*
Infant, Newborn*
Pancreas*
Pancreatic Cyst*
Surgical Procedures, Operative*
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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