| Pancreatic denervation for pain relief in chronic alcohol associated pancreatitis. | |
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MedLine Citation:
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PMID: 2322794 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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To denervate the pancreas of sensory afferents, 15 patients with intractable pain of chronic alcohol induced pancreatitis underwent left transthoracic splanchnicectomy with concomitant bilateral truncal vagotomy. All were malnourished and 11 were addicted to opiates. No respite had been obtained from 33 previous operative procedures. Each patient experienced almost immediate pain relief. Five, however, later had return of pain, but only to the right epigastrium. These five then underwent right transthoracic splanchnicectomy, after which four noted complete and apparently permanent disappearance of pain. In those 14 with a successful outcome there has been a 29 per cent mean increase in body weight, break of hard drug addition in ten of the 11 so afflicted, and return to gainful work or a relatively normal lifestyle in all 14 at a mean follow-up of 16 months. Although 11 of the 14 do have delayed gastric emptying, only one has required a drainage procedure. There have been no other late complications. This approach for control of incapacitating pain in chronic pancreatitis is both safe and simple and at the same time it appears to be reasonably reliable. |
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Authors:
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H H Stone; E J Chauvin |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The British journal of surgery Volume: 77 ISSN: 0007-1323 ISO Abbreviation: Br J Surg Publication Date: 1990 Mar |
Date Detail:
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Created Date: 1990-05-24 Completed Date: 1990-05-24 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0372553 Medline TA: Br J Surg Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 303-5 Citation Subset: AIM; IM |
Affiliation:
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Department of Surgery, Fairview General Hospital, Cleveland, Ohio 44111. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Alcoholism / complications* Female Gastric Emptying / physiology Humans Male Middle Aged Pain, Intractable / etiology, surgery* Pancreas / innervation* Pancreatitis / etiology, physiopathology, surgery* Postoperative Complications / physiopathology Splanchnic Nerves / surgery Sympathectomy* / methods Vagotomy, Truncal |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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