Document Detail

Pancreatic adenosquamous carcinoma presenting as splenic rupture: Report of a case.
MedLine Citation:
PMID:  21626340     Owner:  NLM     Status:  In-Data-Review    
A 58-year-old female patient presented with the sudden onset of left upper quadrant pain. The physical examination revealed the presence of shock status. Abdominal computed tomography revealed splenomegaly with a huge mass inside the spleen, and massive fluid collection in the abdominal cavity. After splenic artery embolization, laparotomy was performed. The operative findings revealed intra-abdominal hemorrhage and rupture of the lower pole of the spleen. Furthermore, a palpable solid mass was observed at the splenic hilum, and distal pancreatectomy with splenectomy was performed. The macroscopic findings revealed a pancreatic tail tumor at the splenic hilum directly invading the splenic parenchyma. Microscopic examinations showed the tumor to consist of squamous cell carcinoma. Furthermore, old and new thrombi were observed inside small splenic arteries. These findings were considered to represent invasion of pancreatic adenosquamous carcinoma to the spleen, and rupture of the spleen was attributed to splenic ischemia resulting from cancer invasion and splenic vein obstruction.
Koji Asai; Manabu Watanabe; Hiroshi Matsukiyo; Akihiro Osawa; Tomoaki Saito; Osahiko Hagiwara; Yoichi Nakamura; Yasushi Okamoto; Yoshihisa Saida; Shinya Kusachi; Yuki Yokouchi; Jiro Nagao
Publication Detail:
Type:  Journal Article     Date:  2011-05-28
Journal Detail:
Title:  Surgery today     Volume:  41     ISSN:  1436-2813     ISO Abbreviation:  Surg. Today     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-05-31     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9204360     Medline TA:  Surg Today     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  872-6     Citation Subset:  IM    
Department of Surgery, Toho University Ohashi Medical Center, 2-17-6 Ohashi, Meguro, Tokyo, 153-8515, Japan.
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