Document Detail

Pancreatic adenocarcinoma: detection and staging with dynamic MR imaging.
MedLine Citation:
PMID:  11335097     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To compare the efficacy of dynamic contrast-enhanced MR imaging and spin-echo T1-weighted with and without fat-saturated MR imaging in the detection and staging of pancreatic adenocarcinoma. METHODS AND MATERIAL: Spin-echo T1-weighted, fat-saturated T1-weighted and dynamic breath-hold 2D-FLASH MR imaging were performed in 25 patients with pancreatic adenocarcinoma. MR images were analysed by calculating the CNR between tumor and normal portion of the pancreas. The CNRs calculated at each sequences were compared. A total of 16 out of 25 patients underwent surgery. Preoperative staging according to TNM classification was also done in patients undergoing surgery. RESULTS: The CNR was significantly different (P<0.05) in the arterial phase of dynamic MR images. The accuracy of 'T' staging was 75% for SE T1-W, fat-saturated T1-W and arterial phase of dynamic MR images. CONCLUSION: The CNRs between pancreatic carcinoma and normal pancreas is significantly higher in dynamic MR sequences than the SE T1-W, fat-saturated T1-W sequences. However, the accuracy of tumor staging according to TNM is equivocal to SE T1-W and fat-saturated T1-W images.
F Obuz; O Dicle; A Coker; O Sağol; S Karademir
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article    
Journal Detail:
Title:  European journal of radiology     Volume:  38     ISSN:  0720-048X     ISO Abbreviation:  Eur J Radiol     Publication Date:  2001 May 
Date Detail:
Created Date:  2001-05-03     Completed Date:  2001-11-01     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8106411     Medline TA:  Eur J Radiol     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  146-50     Citation Subset:  IM    
Dokuz Eylül University School of Medicine, Department of Radiology, Izmir, Turkey.
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MeSH Terms
Adenocarcinoma / pathology*
Magnetic Resonance Imaging* / methods
Middle Aged
Pancreatic Neoplasms / pathology*

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