Document Detail

Pancreatic Adenocarcinoma, version 2.2012: featured updates to the NCCN Guidelines.
MedLine Citation:
PMID:  22679115     Owner:  NLM     Status:  MEDLINE    
The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Pancreatic Adenocarcinoma discuss the workup and management of tumors of the exocrine pancreas. These NCCN Guidelines Insights provide a summary and explanation of major changes to the 2012 NCCN Guidelines for Pancreatic Adenocarcinoma. The panel made 3 significant updates to the guidelines: 1) more detail was added regarding multiphase CT techniques for diagnosis and staging of pancreatic cancer, and pancreas protocol MRI was added as an emerging alternative to CT; 2) the use of a fluoropyrimidine plus oxaliplatin (e.g., 5-FU/leucovorin/oxaliplatin or capecitabine/oxaliplatin) was added as an acceptable chemotherapy combination for patients with advanced or metastatic disease and good performance status as a category 2B recommendation; and 3) the panel developed new recommendations concerning surgical technique and pathologic analysis and reporting.
Margaret A Tempero; J Pablo Arnoletti; Stephen W Behrman; Edgar Ben-Josef; Al B Benson; Ephraim S Casper; Steven J Cohen; Brian Czito; Joshua D I Ellenhorn; William G Hawkins; Joseph Herman; John P Hoffman; Andrew Ko; Srinadh Komanduri; Albert Koong; Wen Wee Ma; Mokenge P Malafa; Nipun B Merchant; Sean J Mulvihill; Peter Muscarella; Eric K Nakakura; Jorge Obando; Martha B Pitman; Aaron R Sasson; Anitra Tally; Sarah P Thayer; Samuel Whiting; Robert A Wolff; Brian M Wolpin; Deborah A Freedman-Cass; Dorothy A Shead;
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Publication Detail:
Type:  Journal Article; Practice Guideline    
Journal Detail:
Title:  Journal of the National Comprehensive Cancer Network : JNCCN     Volume:  10     ISSN:  1540-1413     ISO Abbreviation:  J Natl Compr Canc Netw     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-06-08     Completed Date:  2012-10-31     Revised Date:  2013-11-06    
Medline Journal Info:
Nlm Unique ID:  101162515     Medline TA:  J Natl Compr Canc Netw     Country:  United States    
Other Details:
Languages:  eng     Pagination:  703-13     Citation Subset:  IM    
UCSF Helen Diller Family Comprehensive Cancer Center.
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MeSH Terms
Adenocarcinoma / diagnosis*,  pathology,  therapy*
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Diagnostic Imaging / methods
Neoplasm Staging
Pancreatic Neoplasms / diagnosis*,  pathology,  therapy*
Grant Support
K07 CA140790/CA/NCI NIH HHS; P01 CA117969/CA/NCI NIH HHS; P50 CA127003/CA/NCI NIH HHS

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