Document Detail


Panayiotopoulos syndrome: Probable genetic origin, but not in SCN1A.
MedLine Citation:
PMID:  20813567     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Panayiotopoulos syndrome is encompassed in the classification of the ILAE in idiopathic focal epilepsies. Mutations in the SCN1A gene have been associated with the development of this syndrome. We present two cases of Panayiotopoulos syndrome in two monozygotic twins, who underwent a molecular analysis of SCN1A, but no alteration was found. These cases suggest a genetic origin, and SCN1A appears to be associated with the outcome but not with the development of this syndrome.
Authors:
F Martín Del Valle; A Díaz Negrillo; G Ares Mateos; F J Sanz Santaeufemia; T Del Rosal Rabes; F J González-Valcárcel Sánchez-Puelles
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Publication Detail:
Type:  Journal Article     Date:  2010-09-01
Journal Detail:
Title:  European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society     Volume:  15     ISSN:  1532-2130     ISO Abbreviation:  Eur. J. Paediatr. Neurol.     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-03-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9715169     Medline TA:  Eur J Paediatr Neurol     Country:  England    
Other Details:
Languages:  eng     Pagination:  155-7     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 European Paediatric Neurology Society. Published by Elsevier Ltd. All rights reserved.
Affiliation:
Paediatric Neurology Unit, Paediatric Service, Infanta Elena Hospital, Av Reyes Católicos 21, CP 28340 Valdemoro (Madrid), Spain.
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