Document Detail

Pamidronate results in symptom control of hypertrophic pulmonary osteoarthropathy in cystic fibrosis.
MedLine Citation:
PMID:  11948079     Owner:  NLM     Status:  MEDLINE    
Hypertrophic pulmonary osteoarthropathy (HPOA) may complicate the advanced lung disease that is associated with cystic fibrosis, resulting in severe joint pain and early-morning stiffness. Symptoms are usually controlled with the administration of nonsteroidal anti-inflammatory drugs, physiotherapy, and, on occasions, oral corticosteroids. This report describes a case of refractory HPOA with complete remission following the administration of IV pamidronate, which is a potent inhibitor of osteoclastic bone resorption. Symptom relief resulted for up to 3 months, but repeated courses of pamidronate have been required to maintain symptom control.
Luke A Garske; Scott C Bell
Related Documents :
7327839 - Considerations in determining matching criteria and stratum sizes for case-control stud...
24296269 - Neonatal lupus erythematosis: a five-year case review.
9917119 - Multinational outbreak of salmonella enterica serotype newport infections due to contam...
24392239 - The case of the wandering kidney.
7845919 - Nested case-control studies.
20623659 - New evidence on the health hazards and control of metalworking fluids since completion ...
22381859 - Standardizing the evaluation of scientific and academic performance in neurosurgery - c...
17588019 - Pattern of degenerative ataxias in the eastern province of saudi arabia.
7667489 - Tuberculosis epidemiology in croydon.
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Chest     Volume:  121     ISSN:  0012-3692     ISO Abbreviation:  Chest     Publication Date:  2002 Apr 
Date Detail:
Created Date:  2002-04-11     Completed Date:  2002-05-09     Revised Date:  2006-03-08    
Medline Journal Info:
Nlm Unique ID:  0231335     Medline TA:  Chest     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1363-4     Citation Subset:  AIM; IM    
Adult Cystic Fibrosis Unit and University of Queensland, The Prince Charles Hospital, Brisbane, Australia.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Ankle / radiography
Cystic Fibrosis / drug therapy*,  radiography
Diphosphonates / therapeutic use*
Infusions, Intravenous
Osteoarthropathy, Secondary Hypertrophic / drug therapy*,  radiography
Osteoclasts / drug effects
Reg. No./Substance:
0/Diphosphonates; 40391-99-9/pamidronate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Venous dilatation seen on routine mammography: a clue to superior vena cava obstruction.
Next Document:  Giant cell arteritis presenting with annuloaortic ectasia.