Document Detail


Pamidronate in the treatment of diffuse sclerosing osteomyelitis of the mandible.
MedLine Citation:
PMID:  11740481     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Diffuse sclerosing osteomyelitis of the mandible is characterized by bouts of intense pain, sometimes associated with trismus and paresthesia, and leads to progressive deformity. It is of unknown etiopathology, but it is suggested to be one manifestation of the synovitis, acne, pustulosis, hyperostosis, osteomyelitis syndrome, the other features of which may have been overlooked. Treatment results are disappointing, and decortication may be necessary to achieve an acceptable outcome. We report a case restricted to the mandible that responded favorably to treatment with pamidronate. Further trials of pamidronate in patients with diffuse sclerosing osteomyelitis of the mandible, even in those with the aforementioned syndrome, are needed to assess its effectiveness.
Authors:
M Soubrier; J J Dubost; J M Ristori; B Sauvezie; J L Bussière
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics     Volume:  92     ISSN:  1079-2104     ISO Abbreviation:  Oral Surg Oral Med Oral Pathol Oral Radiol Endod     Publication Date:  2001 Dec 
Date Detail:
Created Date:  2001-12-12     Completed Date:  2002-03-04     Revised Date:  2006-03-08    
Medline Journal Info:
Nlm Unique ID:  9508562     Medline TA:  Oral Surg Oral Med Oral Pathol Oral Radiol Endod     Country:  United States    
Other Details:
Languages:  eng     Pagination:  637-40     Citation Subset:  D; IM    
Affiliation:
Université de Médecine-Hôpital G. Montpied, France.
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MeSH Terms
Descriptor/Qualifier:
Aged
Anti-Inflammatory Agents / therapeutic use*
Diphosphonates / therapeutic use*
Female
Humans
Mandibular Diseases / drug therapy*
Osteomyelitis / drug therapy*
Chemical
Reg. No./Substance:
0/Anti-Inflammatory Agents; 0/Diphosphonates; 40391-99-9/pamidronate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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