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Palmar-plantar erythrodysesthesia associated with chemotherapy and its treatment.
MedLine Citation:
PMID:  21537373     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Palmar-plantar erythrodysesthesia (PPE), also called hand-foot syndrome, is a relatively common dermatologic toxic reaction associated with cytotoxic chemotherapy that can limit the use of such drugs. Definitive prevention and treatment strategies for PPE have not yet been established. We present a patient with recurrent ovarian cancer developing severe hand-foot syndrome after treatment with pegylated liposomal doxorubicin. A review of the relevant literature concerning pathophysiology, preventive measures and management of PPE is given. Electronic search was conducted using the Medline database for English-language records. The search terms used were 'palmar-plantar erythrodysesthesia', 'hand-foot syndrome', 'pegylated liposomal doxorubicin' and 'acral erythema'.
Authors:
Katherina Podlekareva Farr; Akmal Safwat
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Publication Detail:
Type:  Journal Article     Date:  2011-04-11
Journal Detail:
Title:  Case reports in oncology     Volume:  4     ISSN:  1662-6575     ISO Abbreviation:  Case Rep Oncol     Publication Date:  2011  
Date Detail:
Created Date:  2011-05-03     Completed Date:  2011-07-14     Revised Date:  2011-07-28    
Medline Journal Info:
Nlm Unique ID:  101517601     Medline TA:  Case Rep Oncol     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  229-35     Citation Subset:  -    
Affiliation:
Department of Oncology, Aarhus University Hospital, Aarhus, Denmark.
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