| Palmar-plantar erythrodysesthesia associated with scrotal and penile involvement with capecitabine. | |
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MedLine Citation:
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PMID: 17311704 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Capecitabine is an orally active fluoropyrimidine that has been approved for first-line treatment of metastatic colorectal cancer when fluoropyrimidines alone are indicated. One of the toxicities described in the literature associated with capecitabine is palmar-plantar erythrodysesthesia. Based on a careful review of the literature, no reported cases of erythema, ulceration, and swelling that involves the penis and scrotum have been described in association with capecitabine. The following 2 cases illustrate palmar-plantar erythrodysesthesia with scrotal and penile involvement secondary to capecitabine. |
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Authors:
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Christy M Sapp; Philip DeSimone |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Clinical colorectal cancer Volume: 6 ISSN: 1533-0028 ISO Abbreviation: Clin Colorectal Cancer Publication Date: 2007 Jan |
Date Detail:
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Created Date: 2007-02-21 Completed Date: 2007-04-09 Revised Date: 2013-05-28 |
Medline Journal Info:
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Nlm Unique ID: 101120693 Medline TA: Clin Colorectal Cancer Country: United States |
Other Details:
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Languages: eng Pagination: 382-5 Citation Subset: IM |
Affiliation:
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University of Kentucky, Markey Cancer Center, Lexington, KY 40536-0093, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Antimetabolites, Antineoplastic / adverse effects* Colorectal Neoplasms / drug therapy* Deoxycytidine / adverse effects, analogs & derivatives* Erythema / chemically induced* Fluorouracil / adverse effects, analogs & derivatives* Humans Male Middle Aged Penis / drug effects*, pathology Scrotum / drug effects*, pathology |
| Chemical | |
Reg. No./Substance:
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0/Antimetabolites, Antineoplastic; 51-21-8/Fluorouracil; 6804DJ8Z9U/capecitabine; 951-77-9/Deoxycytidine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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