Document Detail


Pallidal deep brain stimulation in the treatment of Meige syndrome.
MedLine Citation:
PMID:  18336624     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Pallidal deep brain stimulation (DBS) of globus pallidus internus (Gpi) has emerged as an effective treatment for dystonia. The experience is however limited concerning focal dystonias and to date only a few cases of pallidal DBS in the treatment of Meige syndrome have been published. METHODS/RESULTS: We here present a patient with Meige syndrome in whom unilateral pallidal DBS failed to improve the axial symptoms, but bilateral stimulation resulted in a major improvement. The Burke-Fahn-Marsden score (BFM) improved by 71.5% and the patient's blepharospasm was abolished. CONCLUSIONS: The results suggest bilateral pallidal DBS may be an effective treatment for Meige syndrome.
Authors:
P Blomstedt; S Tisch; M I Hariz
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-03-11
Journal Detail:
Title:  Acta neurologica Scandinavica     Volume:  118     ISSN:  1600-0404     ISO Abbreviation:  Acta Neurol. Scand.     Publication Date:  2008 Sep 
Date Detail:
Created Date:  2008-09-22     Completed Date:  2008-12-01     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370336     Medline TA:  Acta Neurol Scand     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  198-202     Citation Subset:  IM    
Affiliation:
Department of Neurosurgery, University Hospital of Northern Sweden, Umeå, Sweden. patric.blomstedt@neuro.umu.se
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MeSH Terms
Descriptor/Qualifier:
Adult
Age of Onset
Blepharospasm / etiology
Deep Brain Stimulation*
Dystonia / etiology
Humans
Magnetic Resonance Imaging
Male
Meige Syndrome / complications,  physiopathology,  therapy*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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