| Palladium-Catalyzed Synthesis of Benzimidazoles and Quinazolinones from Common Precursors. | |
| | |
MedLine Citation:
|
PMID: 23030827 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
N-(o-halophenyl)imidoyl chlorides and the corresponding imidates are easily prepared and can be utilised as complementary substrates for the synthesis of important heterocycles. The preparation of N-substituted benzimidazoles was possible from the palladium-catalyzed reaction of both class of substrate with a variety of N-nucleophiles. The use of the imidate precursor for the synthesis of N-substituted quinazolinones by incorporation of a palladium-catalyzed aminocarbonylation reaction has also been demonstrated. Both processes tolerate a wide range of functional groups. |
| | |
Authors:
|
Jessie E R Sadig; Radleigh A A Foster; Florian Wakenhut; Michael C Willis |
Related Documents
:
|
15968057 - Initiation and synthesis of the streptococcus pneumoniae type 3 capsule on a phosphatid... 8156607 - Morphologic and metabolic changes in rat osteoblast cultures during the dark reaction w... 20828127 - Asparagine decarboxylation by lipid oxidation products in model systems. 23347947 - Comparative evaluation of antimicrobials for textile applications. 9703967 - Ebselen, a selenium-containing redox drug, releases zinc from metallothionein. 10814367 - Acetalization of alkenes catalyzed by pd(oac)2/npmov supported on activated carbon unde... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2012-10-3 |
Journal Detail:
|
Title: The Journal of organic chemistry Volume: - ISSN: 1520-6904 ISO Abbreviation: J. Org. Chem. Publication Date: 2012 Oct |
Date Detail:
|
Created Date: 2012-10-3 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 2985193R Medline TA: J Org Chem Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Bi-, Tri-, and Polycyclic Acylphloroglucinols from Hypericum empetrifolium.
Next Document: Electron Attachment to C(7)F(14 ), Thermal Detachment from C(7)F(14)-, The Electron Affinity of C(7)...