| Palatal Insufficiency as Isolated Sign of GQ1b Antibody Syndrome. | |
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MedLine Citation:
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PMID: 21397172 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Antiganglioside GQ1b antibodies mediate a continuum of disorders with overlapping features, fostering the concept of anti-GQ1b antibody syndrome. We present a patient whose palatal insufficiency was the only clinical sign of postinfectious GQ1b antibody syndrome. Cerebral magnetic resonance imaging confirmed involvement of the glossopharyngeal nerve and vagus nerve bilaterally, revealing gadolinium enhancement of both nerves bilaterally and thickening of the left nervus vagus. Magnetic resonance imaging may help in diagnosing postinfectious GQ1b antibody syndrome, especially at early stages and in monosymptomatic patients. Early diagnosis may lead to early therapy, resulting in a milder disease course by preventing further deterioration leading to the ataxia and ophthalmoplegia usually observed in patients with postinfectious GQ1b antibody syndrome. |
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Authors:
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Helene Verhelst; Michaela Maes; Karel Deblaere; Rudy Van Coster |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Pediatric neurology Volume: 44 ISSN: 1873-5150 ISO Abbreviation: Pediatr. Neurol. Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-03-14 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8508183 Medline TA: Pediatr Neurol Country: United States |
Other Details:
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Languages: eng Pagination: 292-4 Citation Subset: IM |
Copyright Information:
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Copyright © 2011 Elsevier Inc. All rights reserved. |
Affiliation:
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Department of Pediatric Neurology, Ghent University Hospital, Ghent, Belgium. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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