Document Detail

Pain is significantly reduced by cryoablation therapy in patients with lateral minithoracotomy.
MedLine Citation:
PMID:  11016387     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: In minimally invasive cardiac surgery use of a lateral minithoracotomy is associated with early postoperative rehabilitation but also relatively high pain levels during the first 3 postoperative days. Cryoablation therapy was evaluated prospectively. METHODS: From April 1999 until September 1999, 57 patients underwent lateral minithoracotomy for mitral valve operation (n = 18) or minimally invasive direct coronary artery bypass grafting (n = 39). Intraoperatively, patients were randomly assigned to cryoablation or intercostal application of local anesthetic agents. A standardized questionnaire was used for prospective pain assessment on postoperative days 1 to 7. RESULTS: From postoperative day 1 to 7 pain levels declined in all groups. Overall pain levels were significantly lower in the cryo group than in the control group (p < 0.0001, GLM). According to diagnoses, pain levels were significantly lower after MIDCABG and cryo versus control; after mitral valve operation they were lower in the cryo group and almost reached significance. CONCLUSIONS: Cryoablation is easy to perform and leads to a significant reduction in pain and lower request for additional pain medication after lateral minithoracotomy in minimally invasive cardiac operation.
J Bucerius; S Metz; T Walther; N Doll; V Falk; A Diegeler; R Autschbach; F W Mohr
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  70     ISSN:  0003-4975     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  2000 Sep 
Date Detail:
Created Date:  2000-10-17     Completed Date:  2000-10-17     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1100-4     Citation Subset:  AIM; IM    
Department of Cardiac Surgery, Heartcenter, University of Leipzig, Germany.
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MeSH Terms
Anesthetics, Local / therapeutic use
Coronary Artery Bypass / methods
Heart Valve Prosthesis Implantation / methods
Middle Aged
Mitral Valve / surgery
Pain, Postoperative / surgery*
Surgical Procedures, Minimally Invasive*
Thoracotomy / methods*
Reg. No./Substance:
0/Anesthetics, Local
Comment In:
Ann Thorac Surg. 2001 Dec;72(6):2180   [PMID:  11789832 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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