| Pain is significantly reduced by cryoablation therapy in patients with lateral minithoracotomy. | |
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MedLine Citation:
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PMID: 11016387 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: In minimally invasive cardiac surgery use of a lateral minithoracotomy is associated with early postoperative rehabilitation but also relatively high pain levels during the first 3 postoperative days. Cryoablation therapy was evaluated prospectively. METHODS: From April 1999 until September 1999, 57 patients underwent lateral minithoracotomy for mitral valve operation (n = 18) or minimally invasive direct coronary artery bypass grafting (n = 39). Intraoperatively, patients were randomly assigned to cryoablation or intercostal application of local anesthetic agents. A standardized questionnaire was used for prospective pain assessment on postoperative days 1 to 7. RESULTS: From postoperative day 1 to 7 pain levels declined in all groups. Overall pain levels were significantly lower in the cryo group than in the control group (p < 0.0001, GLM). According to diagnoses, pain levels were significantly lower after MIDCABG and cryo versus control; after mitral valve operation they were lower in the cryo group and almost reached significance. CONCLUSIONS: Cryoablation is easy to perform and leads to a significant reduction in pain and lower request for additional pain medication after lateral minithoracotomy in minimally invasive cardiac operation. |
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Authors:
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J Bucerius; S Metz; T Walther; N Doll; V Falk; A Diegeler; R Autschbach; F W Mohr |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: The Annals of thoracic surgery Volume: 70 ISSN: 0003-4975 ISO Abbreviation: Ann. Thorac. Surg. Publication Date: 2000 Sep |
Date Detail:
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Created Date: 2000-10-17 Completed Date: 2000-10-17 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 15030100R Medline TA: Ann Thorac Surg Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1100-4 Citation Subset: AIM; IM |
Affiliation:
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Department of Cardiac Surgery, Heartcenter, University of Leipzig, Germany. bucerj@medizin.uni-leipzig.de |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anesthetics, Local
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therapeutic use Coronary Artery Bypass / methods Cryosurgery* Female Heart Valve Prosthesis Implantation / methods Humans Male Middle Aged Mitral Valve / surgery Pain, Postoperative / surgery* Surgical Procedures, Minimally Invasive* Thoracotomy / methods* |
| Chemical | |
Reg. No./Substance:
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0/Anesthetics, Local |
| Comments/Corrections | |
Comment In:
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Ann Thorac Surg. 2001 Dec;72(6):2180
[PMID:
11789832
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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