Document Detail


Pain threshold improvement for chronic hyperacusis patients in a prospective clinical study.
MedLine Citation:
PMID:  19821704     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: The aim of this study was to investigate if laser therapy in combination with pulsed electromagnetic field therapy/repetitive transcranial magnetic stimulation (rTMS) and the control of reactive oxygen species (ROS) would lead to positive treatment results for hyperacusis patients.
BACKGROUND DATA: Eight of the first ten patients treated for tinnitus, who were also suffering from chronic hyperacusis, claimed their hyperacusis improved. Based upon that, a prospective, unblinded, uncontrolled clinical trial was planned and conducted. ROS and hyperacusis pain thresholds were measured.
MATERIALS AND METHODS: Forty-eight patients were treated twice a week with a combination of therapeutic laser, rTMS, and the control and adjustment of ROS. A magnetic field of no more than 100 microT was oriented behind the outer ear, in the area of the mastoid bone. ROS were measured and controlled by administering different antioxidants. At every treatment session, 177-504 J of laser light of two different wavelengths was administered toward the inner ear via meatus acusticus.
RESULTS: The improvements were significantly better in the verum group than in a placebo group, where 40% of the patients were expected to have a positive treatment effect. The patients in the long-term follow-up group received significantly greater improvements than the patients in the short-term follow-up group.
CONCLUSION: The treatment is effective in treating chronic hyperacusis.
Authors:
Michael Zazzio
Related Documents :
15347334 - Epidermal naevi treated with pulsed erbium:yag laser.
16262574 - Low-power laser treatment for shoulder pain.
21183944 - Cost effectiveness of the type ii boston keratoprosthesis.
25285694 - Twenty-year-old stapled pouches for ulcerative colitis without evidence of rectal cance...
23414694 - Does timing of cytoreductive nephrectomy impact patient survival with metastatic renal ...
24494804 - Graft stabilization with cyanoacrylate decreases shrinkage of free gingival grafts.
Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Photomedicine and laser surgery     Volume:  28     ISSN:  1557-8550     ISO Abbreviation:  Photomed Laser Surg     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-06-15     Completed Date:  2010-10-01     Revised Date:  2012-08-28    
Medline Journal Info:
Nlm Unique ID:  101222340     Medline TA:  Photomed Laser Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  371-7     Citation Subset:  IM    
Affiliation:
Audio Laser-Kliniken, Flygeln, Hovmantorp, Sweden. audiolaser@mail.nu
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Aged, 80 and over
Audiometry
Chronic Disease
Combined Modality Therapy
Female
Humans
Hyperacusis / physiopathology*,  therapy*
Laser Therapy
Male
Middle Aged
Pain Threshold*
Prospective Studies
Reactive Oxygen Species
Transcranial Magnetic Stimulation
Treatment Outcome
Young Adult
Chemical
Reg. No./Substance:
0/Reactive Oxygen Species
Comments/Corrections
Comment In:
Photomed Laser Surg. 2012 Jul;30(7):400; author reply 401-2   [PMID:  22742680 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Evaluation of Low-Level Laser Therapy with a He-Ne Laser on the Healing of an Osteochondral Defect u...
Next Document:  Biomodulative Effects of Visible and IR Laser Light on the Healing of Cutaneous Wounds of Nourished ...