Document Detail

Paget's disease of the cervical spine: case report and review.
MedLine Citation:
PMID:  20178006     Owner:  NLM     Status:  In-Data-Review    
STUDY DESIGN: This article presents a case of Paget's disease of the cervical spine.
OBJECTIVES: To report a very rare case of Paget's disease of the cervical spine and review the literature.
METHODS: We report a case of Paget's disease of the cervical spine in a 51-year-old male presenting with neck pain post RTA. Routine radiographs revealed enlarged sclerotic bodies of C2-C5 with normal alignment. CT revealed a fracture of the lateral mass of C2 with extensive sclerotic changes in the bodies of C2-C5 with periosteal apposition, endosteal resorption "pumice stone" type focal periosteal apposition consistent with Paget's disease. Laboratory investigations were consistent with a diagnosis of Paget's disease. Isotope bone scan revealed isolated uptake in the cervical spine. He was commenced on biosphosphonate therapy. Following 12 weeks of immobilisation his orthosis was removed and rehabilitation commenced.
RESULTS: At 12-month follow-up he is asymptomatic with no radiological change.
CONCLUSION: This case illustrates the investigation and successful management of a very rare case of Paget's disease of the cervical spine.
B Lenehan; J Street; N Cassidy
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Publication Detail:
Type:  Journal Article     Date:  2010-02-23
Journal Detail:
Title:  Irish journal of medical science     Volume:  181     ISSN:  1863-4362     ISO Abbreviation:  Ir J Med Sci     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-08-06     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7806864     Medline TA:  Ir J Med Sci     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  369-72     Citation Subset:  IM    
National Spinal Injuries Unit, Mater Misericordiae University Hospital, Dublin, Ireland,
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