Document Detail

Paediatric presentation of familial cerebral cavernoma.
MedLine Citation:
PMID:  19856389     Owner:  NLM     Status:  MEDLINE    
We report the case of a 13-year-old male who presented with headaches and was presumed to have a brain tumour. He was subsequently found to have multiple cerebral cavernomas with haemorrhage and positive family history. We review the literature on familial cavernomas. Cerebral cavernous malformations (CCMs) are characterized by abnormally enlarged capillary cavities without intervening brain parenchyma [Verlaan et al. Neurology 2005; 65:1982-1983] that may involve any part of the central nervous system. Focal neurologic deficit and haemorrhage occur in 45% of children, higher than in adults [Stoeter. Neurosurg Rev 2001; 24]. Paediatric patients with symptomatic cavernous malformations should be treated surgically because of the risk of haemorrhage [Lee et al. Child's Nervous Syst 2008; 24:321-327].
Harriet Holme; Vasanta Nanduri
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pediatric blood & cancer     Volume:  54     ISSN:  1545-5017     ISO Abbreviation:  Pediatr Blood Cancer     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-01-15     Completed Date:  2010-02-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101186624     Medline TA:  Pediatr Blood Cancer     Country:  United States    
Other Details:
Languages:  eng     Pagination:  468-9     Citation Subset:  IM    
Copyright Information:
Copyright 2009 Wiley-Liss, Inc.
Watford General Hospital, Watford, UK.
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MeSH Terms
Brain Neoplasms / diagnosis
Diagnosis, Differential
Hemangioma, Cavernous, Central Nervous System / diagnosis*

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