| Paediatric oral peanut challenges: a comparison of practice in London and Western Switzerland. | |
| | |
MedLine Citation:
|
PMID: 23347121 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
BACKGROUND: There are guidelines on how to develop a food challenge protocol, but at present there is no gold standard guidance on method, and separate units produce differing protocols. METHODS: We performed a retrospective analysis of 200 patients' data from the paediatric allergy units in Lausanne and Geneva, Western Switzerland, and St Thomas' Hospital (STH), UK. RESULTS: St Thomas' Hospital has a younger cohort with a lower overall mean spIgE (2.36 kU/l vs 8.00 kU/l, P = 0.004). The target peanut protein volumes differed: Switzerland 4.4 g vs STH 8.4 g. Despite this, the dose actually achieved in positive challenges was not significantly different (2.33 g vs 1.49 g, P = 0.16). 26% of challenges reacted at 4 g or more of peanut protein. CONCLUSIONS: The differences in results highlight how the variation in reasoning behind food challenge alters the outcome. Standardization of food challenges would allow easy comparison between hospitals and geographical areas for research purposes. |
| | |
Authors:
|
S Ludman; J Wassenberg; G Du Toit; A T Fox; G Lack; P A Eigenmann |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2013-1-25 |
Journal Detail:
|
Title: Allergy Volume: - ISSN: 1398-9995 ISO Abbreviation: Allergy Publication Date: 2013 Jan |
Date Detail:
|
Created Date: 2013-1-25 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 7804028 Medline TA: Allergy Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
© 2013 John Wiley & Sons A/S. Published by Blackwell Publishing Ltd. |
Affiliation:
|
Allergy, Immunology and Rheumatology Unit, University Hospital, Lausanne, Switzerland. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Measuring Oral Direct Inhibitors (ODIs) of thrombin and factor Xa: A recommendation from the Subcomm...
Next Document: Many apples a day keep the blues away - Daily experiences of negative and positive affect and food c...