Document Detail

Paclitaxel- and/or cisplatin-induced ocular neurotoxicity: a case report and literature review.
MedLine Citation:
PMID:  25114574     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Paclitaxel (PTX) and/or cisplatin (CDDP), as important cytotoxic anti-cancer agents, are widely used to treat various solid tumors. Both may cause moderate or severe neurotoxicity, but ocular neurotoxicity is also occasionally reported. A patient diagnosed with nasopharyngeal cancer suffering acute ocular neurotoxicity 10 days after paclitaxel and CDDP administration at the recommended dose is described in the present case report, and PTX- and/or CDDP-induced ocular neurotoxicity are summarized according to previous reports. Possible mechanisms and the potential diagnostic, therapeutic and predictive strategies of PTX- and/or CDDP-induced ocular neurotoxicity are reviewed, to help the oncologist to take the infrequent toxicity of cytotoxic drugs into account and improve patient safety during anti-cancer therapy.
Ying Li; Yanping Li; Junyu Li; Guoliang Pi; Wenyong Tan
Related Documents :
23448594 - Endolymphatic sac tumour: case report and literature review.
12637064 - Recurrent subarachnoid haemorrhage from a de novo basilar bifurcation aneurysm: a case ...
15004584 - The earliest case of retinopathy of prematurity?
17600994 - Moulded cement-prosthesis for osteosarcoma of the proximal humerus.
22052624 - Systematic review of the epidemiology of systemic lupus erythematosus in asia-pacific: ...
23951834 - Upper gastrointestinal bleeding from gastric splenosis; a case report and literature re...
Publication Detail:
Type:  Journal Article     Date:  2014-07-31
Journal Detail:
Title:  OncoTargets and therapy     Volume:  7     ISSN:  1178-6930     ISO Abbreviation:  Onco Targets Ther     Publication Date:  2014  
Date Detail:
Created Date:  2014-08-12     Completed Date:  2014-08-12     Revised Date:  2014-08-15    
Medline Journal Info:
Nlm Unique ID:  101514322     Medline TA:  Onco Targets Ther     Country:  New Zealand    
Other Details:
Languages:  eng     Pagination:  1361-6     Citation Subset:  -    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  PD-1 as an emerging therapeutic target in renal cell carcinoma: current evidence.
Next Document:  Lapatinib for the treatment of breast cancer in the People's Republic of China.