Document Detail


Packing efficacy of hydrocoil embolic system: in vitro study using ruptured aneurysm model.
MedLine Citation:
PMID:  17323099     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
After endovascular coil embolization of cerebral aneurysms, coil compaction and late aneurysm recanalization have been ever observed. The HydroCoil Embolic System (HES) was developed to improve the packing efficacy of endovascular treatment of cerebral aneurysms. In this study, we evaluate the packing efficacy of HES using a silicone model of ruptured cerebral aneurysm. This silicone model was connected to a pulsatile flow pump and embolized with the initial framing coils followed by hydro coils (n = 3) or bare platinum coils (n = 3). The coils used in the two groups were identical to each other in size and length. In the hydro coil group, continuous outflow from ruptured aneurysm ceased in two out of three cases. On the other hand, in the bare platinum coil group, outflow from the ruptured point slightly decreased but did not stop in all cases. The hydro coil could result in a higher initial occlusion rate of silicone model. In addition, expanded hydrogel possibly sealed the ruptured point directly. Changes in the size of aneurysms were not detected, from which the risk of over-expansion seemed extremely low. The hydro Coil is a safe and feasible device for improving the packing efficacy in endovascular coil embolization.
Authors:
Kyoichi Watanabe; Kenji Sugiu; Koji Tokunaga; Wataru Sasahara; Shigeki Ono; Isao Date
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2007-02-24
Journal Detail:
Title:  Neurosurgical review     Volume:  30     ISSN:  0344-5607     ISO Abbreviation:  Neurosurg Rev     Publication Date:  2007 Apr 
Date Detail:
Created Date:  2007-03-08     Completed Date:  2007-06-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7908181     Medline TA:  Neurosurg Rev     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  127-30; discussion 130     Citation Subset:  IM    
Affiliation:
Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Science, Okayama 700-8558, Japan.
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MeSH Terms
Descriptor/Qualifier:
Aneurysm, Ruptured / therapy*
Angioplasty*
Embolization, Therapeutic / instrumentation*
Equipment Design
Feasibility Studies
Humans
Hydrogel
Intracranial Aneurysm / therapy*
Models, Cardiovascular
Treatment Outcome
Chemical
Reg. No./Substance:
25852-47-5/Hydrogel

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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