Document Detail


Pachydermatous eosinophilic dermatitis.
MedLine Citation:
PMID:  21489364     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A case is presented of a female Caucasian patient with chronic peripheral blood eosinophilia and unusual skin manifestations. Within a couple of years, the patient developed multiple hyperkeratotic and hyperpigmented papules and plaques all over the body, palmoplantar keratoderma, pachydermia of acral parts of the body, and generalized pruritus. Generalized lymphadenopathy appeared. Other relevant symptoms were persistent peripheral blood hypereosinophilia and increased level of total IgE. The patient was diagnosed with a very rare condition, pachydermatous eosinophilic dermatitis, and was administered combined therapy with dapsone, oral methylprednisolone and fexophenadine. After one month of treatment, the skin changes markedly improved.
Authors:
Joanna Salomon; Rafał Białynicki-Birula; Zdzisław Woźniak; Eugeniusz Baran
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Acta dermatovenerologica Croatica : ADC     Volume:  19     ISSN:  1847-6538     ISO Abbreviation:  Acta Dermatovenerol Croat     Publication Date:  2011  
Date Detail:
Created Date:  2011-04-14     Completed Date:  2011-08-19     Revised Date:  2012-08-31    
Medline Journal Info:
Nlm Unique ID:  9433781     Medline TA:  Acta Dermatovenerol Croat     Country:  Croatia    
Other Details:
Languages:  eng     Pagination:  31-5     Citation Subset:  IM    
Affiliation:
Department of Dermatology, Venereology and Allergology, Wroclaw Medical University, Poland. jsalomon@op.pl
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MeSH Terms
Descriptor/Qualifier:
Acitretin / therapeutic use
Adrenal Cortex Hormones / therapeutic use
Adult
Biopsy, Needle
Dermatitis / drug therapy*,  pathology*,  physiopathology
Drug Therapy, Combination
Eosinophilia / drug therapy*,  pathology*,  physiopathology
Female
Follow-Up Studies
Histamine Antagonists / therapeutic use
Humans
Immunohistochemistry
Keratoderma, Palmoplantar / drug therapy,  pathology,  physiopathology
Keratosis / drug therapy,  pathology,  physiopathology
Risk Assessment
Severity of Illness Index
Treatment Outcome
Chemical
Reg. No./Substance:
0/Adrenal Cortex Hormones; 0/Histamine Antagonists; 55079-83-9/Acitretin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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