Document Detail

PVC flooring is related to human uptake of phthalates in infants.
MedLine Citation:
PMID:  22563949     Owner:  NLM     Status:  Publisher    
Poly Vinyl Chloride (PVC) flooring material contains phthalates and it has been shown that such materials are important sources for phthalates in indoor dust. Phthalates are suspected endocrine disrupting chemicals (EDCs). Consecutive infants between two and six months old and their mothers were invited. A questionnaire about indoor environmental factors and family life style was used. Urinary metabolites of the phthalates di-ethyl phthalate (DEP), di-butyl phthalate (DBP), butylbenzyl phthalate (BBzP) and di-etylhexyl phthalate (DEHP) were measured in the urine of the children. Of 209 invited children, 110 (52%) participated. Urine samples were obtained from 83 of these. Urine levels of the BBzP metabolite monobenzyl phthalate (MBzP) was significantly higher in infants with PVC flooring in their bedrooms (p<0.007) and related to the body area of the infant. Levels of the DEHP metabolites MEHHP (p<0.01) and MEOHP (p<0.04) were higher in the two months old infants who were not exclusively breastfed when compared with breastfed children. The findings indicate that the use of soft PVC as flooring material may increase the human uptake of phthalates in infants. Urinary levels of phthalate metabolites during early life are associated to the use of PVC flooring in the bedroom, body area and the use of infant formula. © 2012 John Wiley & Sons A/S.
Fredrik Carlstedt; Bo Ag Jönsson; Carl-Gustaf Bornehag
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-5-7
Journal Detail:
Title:  Indoor air     Volume:  -     ISSN:  1600-0668     ISO Abbreviation:  -     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-5-8     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9423515     Medline TA:  Indoor Air     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2012 John Wiley & Sons A/S.
Primary Care Research Centre, County Council of Värmland, Universitetsgatan 3, S-656 37 KARLSTAD, Sweden. Division of Occupational and Environmental Medicine, Department of Laboratory Medicine, Lund, Lund University, S-221 85, Lund, Sweden. Public Health Sciences, Karlstad University, Universitetsgatan 1, S-651 88 Karlstad, Sweden.
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