Document Detail

PSA levels in men with spinal cord injury and under intermittent catheterization.
MedLine Citation:
PMID:  21661042     Owner:  NLM     Status:  MEDLINE    
AIM: To evaluate serum PSA levels of patients with spinal cord injury (SCI) submitted or not to CIC in comparison to those of the general population.
METHODS: We retrospectively studied 140 men with SCI admitted in our department from January 2005 to May 2009. Thirty-four SCI patients had PSA levels available, comprising 21 under CIC and 13 without CIC. Patients under CIC performed it 4-6 times a day and mean time of catheterization was 72.4 months (range 30-192). The most common etiology of SCI was fall from height (33%), followed by car/motorcycle crashes (15%). Control group was composed by 670 healthy men that were referred to our service to evaluation of Kidney donation or cancer prostate screening. We used Student's t-test and variance analysis (ANOVA) for age and PSA comparison between the groups.
RESULTS: Overall, patients with SCI and controls had similar mean age (54 vs. 57 years old, P = 0.11) and mean PSA level (1.81 vs. 1.95  ng/ml, P = 0.66). SCI patients were divided into with and without CIC. Patients without CIC had similar mean age (60 vs. 57 years old, P = 0.11) and similar PSA values when compared to controls (1.72 vs. 1.95  ng/ml, P = 0.89). Patients under CIC were compared to controls with similar age (50 vs. 47 years, P = 0.0332) and their PSA levels were greater (1.86 vs. 0.79  ng/ml, P = 0.026).
CONCLUSION: Clean intermittent catheterization increased PSA levels approximately doubling its value.
Fabio César Miranda Torricelli; Marcos Lucon; Fabio Vicentini; Cristiano Mendes Gomes; Miguel Srougi; Homero Bruschini
Publication Detail:
Type:  Journal Article     Date:  2011-06-09
Journal Detail:
Title:  Neurourology and urodynamics     Volume:  30     ISSN:  1520-6777     ISO Abbreviation:  Neurourol. Urodyn.     Publication Date:  2011 Nov 
Date Detail:
Created Date:  2011-10-20     Completed Date:  2012-02-10     Revised Date:  2012-04-23    
Medline Journal Info:
Nlm Unique ID:  8303326     Medline TA:  Neurourol Urodyn     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1522-4     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Wiley Periodicals, Inc.
Hospital das Clínicas, Division of Urology, University of São Paulo Medical School, São Paulo, SP, Brazil.
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MeSH Terms
Analysis of Variance
Intermittent Urethral Catheterization* / adverse effects
Middle Aged
Prostate-Specific Antigen / blood*
Retrospective Studies
Spinal Cord Injuries / blood,  complications*
Time Factors
Urinary Bladder, Neurogenic / blood,  etiology,  therapy*
Urinary Incontinence / blood,  etiology,  therapy*
Reg. No./Substance:
EC Antigen
Comment In:
J Urol. 2012 Apr;187(4):1359   [PMID:  22423933 ]

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