| PSA levels in men with spinal cord injury and under intermittent catheterization. | |
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MedLine Citation:
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PMID: 21661042 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIM: To evaluate serum PSA levels of patients with spinal cord injury (SCI) submitted or not to CIC in comparison to those of the general population. METHODS: We retrospectively studied 140 men with SCI admitted in our department from January 2005 to May 2009. Thirty-four SCI patients had PSA levels available, comprising 21 under CIC and 13 without CIC. Patients under CIC performed it 4-6 times a day and mean time of catheterization was 72.4 months (range 30-192). The most common etiology of SCI was fall from height (33%), followed by car/motorcycle crashes (15%). Control group was composed by 670 healthy men that were referred to our service to evaluation of Kidney donation or cancer prostate screening. We used Student's t-test and variance analysis (ANOVA) for age and PSA comparison between the groups. RESULTS: Overall, patients with SCI and controls had similar mean age (54 vs. 57 years old, P = 0.11) and mean PSA level (1.81 vs. 1.95 ng/ml, P = 0.66). SCI patients were divided into with and without CIC. Patients without CIC had similar mean age (60 vs. 57 years old, P = 0.11) and similar PSA values when compared to controls (1.72 vs. 1.95 ng/ml, P = 0.89). Patients under CIC were compared to controls with similar age (50 vs. 47 years, P = 0.0332) and their PSA levels were greater (1.86 vs. 0.79 ng/ml, P = 0.026). CONCLUSION: Clean intermittent catheterization increased PSA levels approximately doubling its value. |
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Authors:
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Fabio César Miranda Torricelli; Marcos Lucon; Fabio Vicentini; Cristiano Mendes Gomes; Miguel Srougi; Homero Bruschini |
Publication Detail:
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Type: Journal Article Date: 2011-06-09 |
Journal Detail:
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Title: Neurourology and urodynamics Volume: 30 ISSN: 1520-6777 ISO Abbreviation: Neurourol. Urodyn. Publication Date: 2011 Nov |
Date Detail:
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Created Date: 2011-10-20 Completed Date: 2012-02-10 Revised Date: 2012-04-23 |
Medline Journal Info:
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Nlm Unique ID: 8303326 Medline TA: Neurourol Urodyn Country: United States |
Other Details:
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Languages: eng Pagination: 1522-4 Citation Subset: IM |
Copyright Information:
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Copyright © 2011 Wiley Periodicals, Inc. |
Affiliation:
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Hospital das Clínicas, Division of Urology, University of São Paulo Medical School, São Paulo, SP, Brazil. fabio_torri@yahoo.com.br |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Analysis of Variance Brazil Humans Intermittent Urethral Catheterization* / adverse effects Male Middle Aged Prostate-Specific Antigen / blood* Retrospective Studies Spinal Cord Injuries / blood, complications* Time Factors Up-Regulation Urinary Bladder, Neurogenic / blood, etiology, therapy* Urinary Incontinence / blood, etiology, therapy* |
| Chemical | |
Reg. No./Substance:
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EC 3.4.21.77/Prostate-Specific Antigen |
| Comments/Corrections | |
Comment In:
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J Urol. 2012 Apr;187(4):1359
[PMID:
22423933
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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