Document Detail

Is PRP useful in alveolar cleft reconstruction? Platelet-rich plasma in secondary alveoloplasty.
MedLine Citation:
PMID:  20038881     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Cleft lip and palate is a congenital facial malformation with an established treatment protocol. Mixed dentition period is the best moment for correct maxillary bone defect with an alveoloplasty. The aim of this surgical procedure is to facilitate dental eruption, re-establish maxillary arch, close any oro-nasal communication, give support to nasal ala, and in some cases allow dental rehabilitation with osteointegrated implants.
STUDY DESIGN: Twenty cleft patients who underwent secondary alveoloplasty were included. In 10 of them autogenous bone graft were used and in other 10 autogenous bone and platelet-rich plasma (PRP) obtained from autogenous blood. Bone formation was compared by digital orthopantomography made on immediate post-operatory and 3 and 6 months after the surgery.
RESULTS: No significant differences were found between both therapeutic groups on bone regeneration.
CONCLUSION: We do not find justified the use of PRP for alveoloplasty in cleft patients' treatment protocol.
Ramon Luaces-Rey; Jorge Arenaz-Búa; José-Luis Lopez-Cedrún-Cembranos; Susana Herrero-Patiño; Sheyla Sironvalle-Soliva; Emma Iglesias-Candal; María Pombo-Castro
Publication Detail:
Type:  Journal Article     Date:  2010-07-01
Journal Detail:
Title:  Medicina oral, patología oral y cirugía bucal     Volume:  15     ISSN:  1698-6946     ISO Abbreviation:  Med Oral Patol Oral Cir Bucal     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-07-01     Completed Date:  2010-12-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101231694     Medline TA:  Med Oral Patol Oral Cir Bucal     Country:  Spain    
Other Details:
Languages:  eng     Pagination:  e619-23     Citation Subset:  D; IM    
Servicio de Cirugia Maxilofacial, Complexo Hospitalario A Coruña, As Xubias 84, 15006, A Coruña, Spain.
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MeSH Terms
Alveoloplasty* / methods
Bone Regeneration
Bone Transplantation*
Cleft Lip / surgery*
Cleft Palate / surgery*
Combined Modality Therapy
Platelet-Rich Plasma*

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