Document Detail

PQ Segment Depression in Short QT Syndrome Patients: A Novel Marker for Diagnosing Short QT Syndrome?: Short QT Syndrome and PQ Segment Depression.
MedLine Citation:
PMID:  24589867     Owner:  NLM     Status:  Publisher    
BACKGROUND: Patients with a short QT syndrome (SQTS) have an increased risk for atrial, ventricular tachyarrhythmias and/or sudden cardiac death. PQ segment depression (PQD) is related to atrial fibrillation and carries a poor prognosis in the setting of acute inferior myocardial infarction and is a well defined ECG marker of acute pericarditis.
OBJECTIVES: The aim of this study was to evaluate the prevalence of PQD in SQTS and to analyze the association with atrial arrhythmias.
METHODS: 12-lead ECGs of SQTS patients were evaluated for PQD in all leads and for QT intervals in lead II and V5. PQD was defined as ≥ 0.05 mV (0.5 mm) depression from the isoelectric line.
RESULTS: A total of 760 leads from 64 SQTS patients [mean age 36 ± 18 years, 48 males (75%)] were analyzed. PQD was seen in 265 (35%) leads from 52 (81%) patients and was more frequent in leads II, V3, aVF, V4, and I [n=43 (67%), n=30 (47%), n=27 (42%), n=25 (39%), n=25 (39%), respectively]. Nine of 64 patients (14%) presented with atrial tachyarrhythmias and all of them had PQD.
CONCLUSIONS: two of 64 patients (81%) with SQTS reveal PQD. As PQD is rarely observed in healthy subjects, this ECG stigma may constitute a novel marker for SQTS in addition to a short QT interval.
Erol Tülümen; Carla Giustetto; C Christian Wolpert; Philippe Maury; Olli Anttonen; Vincent Probst; Jean-Jacques Blanc; Pascal Sbragia; Chiara Scrocco; Boris Rudic; Christian Veltmann; Yaxun Sun; Fiorenzo Gaita; Charles Antzelevitch; Martin Borggrefe; Rainer Schimpf
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-2-28
Journal Detail:
Title:  Heart rhythm : the official journal of the Heart Rhythm Society     Volume:  -     ISSN:  1556-3871     ISO Abbreviation:  Heart Rhythm     Publication Date:  2014 Feb 
Date Detail:
Created Date:  2014-3-4     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101200317     Medline TA:  Heart Rhythm     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2014. Published by Elsevier Inc.
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