| PPARs: Fatty acid sensors controlling metabolism. | |
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MedLine Citation:
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PMID: 22273692 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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The peroxisome proliferator activated receptors (PPARs) are nuclear receptors that play key roles in the regulation of lipid metabolism, inflammation, cellular growth, and differentiation. The receptors bind and are activated by a broad range of fatty acids and fatty acid derivatives and they thereby serve as major transcriptional sensors of fatty acids. Here we review the function, regulation, and mechanism of the different PPAR subtypes with special emphasis on their role in the regulation of lipid metabolism. |
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Authors:
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Lars la Cour Poulsen; Majken Siersbæk; Susanne Mandrup |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-1-18 |
Journal Detail:
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Title: Seminars in cell & developmental biology Volume: - ISSN: 1096-3634 ISO Abbreviation: - Publication Date: 2012 Jan |
Date Detail:
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Created Date: 2012-1-25 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9607332 Medline TA: Semin Cell Dev Biol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2012. Published by Elsevier Ltd. |
Affiliation:
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University of Southern Denmark, Department of Biochemistry and Molecular Biology, Campusvej 55, DK-5230, Odense M, Denmark. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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