Document Detail


POEMS syndrome revealed by multiple glomeruloid angiomas.
MedLine Citation:
PMID:  12077535     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, skin disorders) is a rare multisystemic disease associated with plasma cell dyscrasia. A 68-year-old woman with chronic renal insufficiency and arterial hypertension included in her medical history was admitted to the hospital with confusion, somnolence and asthenia. She presented ascites, hepatosplenomegaly, leg oedema, distal dysesthesias, leuconychia and multiple nodular purple red angiomas on the trunk, upper limbs and fingers. Hypothyroidism was revealed in the laboratory investigations and monoclonal IgG peak in immunoelectrophoresis. Electromyography showed both demyelinisating and axonal degenerative neuropathy. The diagnosis of POEMS syndrome was based on the dermatopathological examination of a cutaneous angioma; histology revealed features of glomeruloid angioma, a specific marker of this syndrome.
Authors:
Christel Scheers; Athanassios Kolivras; Alexandra Corbisier; Patrick Gheeraert; Charles Renoirte; Anne Theunis; Nicolas de Saint-Aubain; Josette André; Ursula Sass; Micheline Song
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Dermatology (Basel, Switzerland)     Volume:  204     ISSN:  1018-8665     ISO Abbreviation:  Dermatology (Basel)     Publication Date:  2002  
Date Detail:
Created Date:  2002-06-21     Completed Date:  2002-09-26     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9203244     Medline TA:  Dermatology     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  311-4     Citation Subset:  IM    
Copyright Information:
Copyright 2002 S. Karger AG, Basel
Affiliation:
Department of Dermatology, CHU Saint-Pierre and CHU Brugmann, Brussels, Belgium. christel_email@yahoo.com
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MeSH Terms
Descriptor/Qualifier:
Aged
Diagnosis, Differential
Fatal Outcome
Female
Hemangioma / etiology
Humans
POEMS Syndrome / complications,  diagnosis*

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