Document Detail


POEMS syndrome, osteosclerotic myeloma and Castleman's disease: a case report.
MedLine Citation:
PMID:  1953537     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Peripheral neuropathy, organomegaly, endocrinopathy, monoclonal gammopathy and skin changes are often the presenting features of the POEMS syndrome. Approximately 50% of these are associated with osteosclerotic myeloma, a rare variant of multiple myeloma and some with Castleman's disease, an unusual lympho-proliferative disorder. The underlying pathogenetic mechanisms have not been elucidated but amelioration of symptoms with the disappearance of the M-component suggests possible etiopathogenic mechanisms. We present a 40-year-old woman with manifestations of all three disorders.
Authors:
J Bosco; R Pathmanathan
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Australian and New Zealand journal of medicine     Volume:  21     ISSN:  0004-8291     ISO Abbreviation:  Aust N Z J Med     Publication Date:  1991 Aug 
Date Detail:
Created Date:  1991-11-27     Completed Date:  1991-11-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  1264322     Medline TA:  Aust N Z J Med     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  454-6     Citation Subset:  IM    
Affiliation:
Department of Medicine, University of Malaya, Kuala Lumpur.
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MeSH Terms
Descriptor/Qualifier:
Adult
Bone Neoplasms / complications*,  pathology
Female
Giant Lymph Node Hyperplasia / complications*,  pathology
Humans
Multiple Myeloma / complications*,  pathology
POEMS Syndrome / complications*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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