| PICS-ure this: prosenescence therapy? | |
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MedLine Citation:
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PMID: 20227036 Owner: NLM Status: PubMed-not-MEDLINE |
Abstract/OtherAbstract:
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Senescence is increasingly recognized as a critical feature of mammalian cells to suppress tumorigenesis, acting together with cell death programs. Whether senescence, like programmed cell death, can be exploited therapeutically has been unclear. Pandolfi and coworkers now propose that PTEN-loss-induced cellular senescence (PICS) may be triggered in vivo for therapy. |
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Authors:
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Daniel S Peeper |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Cancer cell Volume: 17 ISSN: 1878-3686 ISO Abbreviation: Cancer Cell Publication Date: 2010 Mar |
Date Detail:
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Created Date: 2010-03-15 Completed Date: 2010-06-30 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101130617 Medline TA: Cancer Cell Country: United States |
Other Details:
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Languages: eng Pagination: 219-20 Citation Subset: - |
Copyright Information:
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Copyright 2010 Elsevier Inc. All rights reserved. |
Affiliation:
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The Netherlands Cancer Institute, Division of Molecular Genetics, 1066 CX Amsterdam, the Netherlands. d.peeper@nki.nl |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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