Document Detail


Medicine management: pharmacokinetic update for community nurses.
MedLine Citation:
PMID:  20852525     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Medication management is a major part of nursing practice. Ensuring safety in medication management is all the more important in the community, where patients are not under constant observation of a health-care professional. One of the prime factors in maintaining safety with medication is establishing and maintaining adequate and safe drug levels in the body. Before drugs can have an effect, they are acted upon by the body; these processes change the drug, mainly to enhance its removal from the body. Study of these processes is called pharmacokinetics and includes the processes of absorption, distribution, metabolism and excretion. Pharmacokinetic processes determine the time of onset and duration of drug action. In turn drug pharmacokinetics is affected by concordance with medication regimes and systemic illness; factors which may render the medication useless or toxic. This article introduces the reader to the principles of pharmacokinetics and shows the link between pharmacokinetics and disease and administration of multiple drugs (polypharmacy). With an aim to equip the community nurse with a better understanding of how to recognize and foresee problems associated with medication management.
Authors:
Ehsan Khan
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British journal of community nursing     Volume:  15     ISSN:  1462-4753     ISO Abbreviation:  Br J Community Nurs     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-09-20     Completed Date:  2010-12-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9815827     Medline TA:  Br J Community Nurs     Country:  England    
Other Details:
Languages:  eng     Pagination:  436-44     Citation Subset:  N    
Affiliation:
Florence Nightingale School of Nursing and Midwifery, King's College London.eu.khan@kcl.ac.uk
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MeSH Terms
Descriptor/Qualifier:
Blood Proteins / physiology
Community Health Nursing / education,  methods*
Drug Monitoring / methods,  nursing
Drug Therapy / adverse effects,  nursing*
Gastric Acid / physiology
Humans
Hydrogen-Ion Concentration
Intestinal Absorption / physiology
Kidney / physiology
Pharmacokinetics*
Polypharmacy
Safety
Skin Absorption / physiology
Skin Physiological Phenomena
Solubility
Tissue Distribution / physiology
Chemical
Reg. No./Substance:
0/Blood Proteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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