Document Detail

The PHANTASTICA gene encodes a MYB transcription factor involved in growth and dorsoventrality of lateral organs in Antirrhinum.
MedLine Citation:
PMID:  9630222     Owner:  NLM     Status:  MEDLINE    
The organs of a higher plant show two fundamental axes of asymmetry: proximodistal and dorsoventral. Dorsoventrality in leaves, bracts, and petal lobes of Antirrhinum majus requires activity of the PHANTASTICA (PHAN) gene. Conditional mutants revealed that PHAN is also required for earlier elaboration of the proximodistal axis. PHAN was isolated and shown to encode a MYB transcription factor homolog. PHAN mRNA is first detected in organ initials before primordium initiation. The structure and expression pattern of PHAN, together with its requirement in two key features of organ development, are consistent with a role in specifying lateral organ identity as distinct from that of the stem or meristem. PHAN also appears to maintain meristem activity in a non-cell-autonomous manner.
R Waites; H R Selvadurai; I R Oliver; A Hudson
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Cell     Volume:  93     ISSN:  0092-8674     ISO Abbreviation:  Cell     Publication Date:  1998 May 
Date Detail:
Created Date:  1998-07-06     Completed Date:  1998-07-06     Revised Date:  2006-11-20    
Medline Journal Info:
Nlm Unique ID:  0413066     Medline TA:  Cell     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  779-89     Citation Subset:  IM    
Institute of Cell and Molecular Biology, University of Edinburgh, United Kingdom.
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MeSH Terms
Amino Acid Sequence
Angiosperms / genetics,  growth & development*
Base Sequence
Cloning, Molecular
DNA-Binding Proteins / genetics*
Genes, Plant*
In Situ Hybridization
Meristem / genetics,  growth & development
Molecular Sequence Data
Plant Proteins / genetics*
Plant Shoots / genetics,  growth & development*
Proto-Oncogene Proteins c-myb*
RNA, Messenger / isolation & purification
RNA, Plant / isolation & purification
Sequence Homology, Amino Acid
Tissue Distribution
Transcription Factors / genetics*
Reg. No./Substance:
0/DNA-Binding Proteins; 0/Plant Proteins; 0/Proto-Oncogene Proteins c-myb; 0/RNA, Messenger; 0/RNA, Plant; 0/Transcription Factors

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