| PET versus PET-CT in patient with suspicion of non-Hodgkin lymphoma recurrence. | |
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MedLine Citation:
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PMID: 18030052 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We present the case of a 62-year-old patient with a history of non-Hodgkin lymphoma (stage III) in complete remission after 6 cycles of cyclophosphamide, doxorubicin, vincristine, and prednisone with rituximab (CHOP-R) in 2006. The patient was referred for a PET-CT scan because of suspicion of recurrence. On PET there were multiple lung lesions, a submandibular lesion (right side) and an impressive retroperitoneal mass with a hypermetabolic wall, and central necrosis invading all retroperitoneal structures (aorta). There was also an additional lesion in the anterior abdominal wall below the liver. It was concluded that it was recurrent non-Hodgkin lymphoma (stage IV). Contrast enhanced CT demonstrated a large, rupturing abdominal aortic aneurysm (AAA) with saccular ectasia of the posterior wall compatible with a mycotic aneurysm. The other sites of hypermetabolism corresponded to metastatic infectious lesions. Histopathology confirmed the mycotic infection. The patient underwent urgent surgery including bilateral axillofemoral stenting and removing a clot from the AAA twice. Intravenous antibiotics were started. This case clearly denotes the importance of contrast enhanced hybrid PET-CT systems in which the CT information is relevant for PET interpretation and not only for anatomic repair. With PET alone, the diagnosis would have been completely different. |
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Authors:
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Gerard Moulin-Romsee; Luc Mortelmans |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Clinical nuclear medicine Volume: 32 ISSN: 0363-9762 ISO Abbreviation: Clin Nucl Med Publication Date: 2007 Dec |
Date Detail:
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Created Date: 2007-11-21 Completed Date: 2008-02-06 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7611109 Medline TA: Clin Nucl Med Country: United States |
Other Details:
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Languages: eng Pagination: 954-5 Citation Subset: IM |
Affiliation:
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Department of Nuclear Medicine, UZ Gasthuisberg, KU Leuven, Belgium. gmromsee@hotmail.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aneurysm, Infected
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etiology*,
pathology,
radiography Aneurysm, Ruptured / etiology, pathology, radiography* Aortic Aneurysm, Abdominal / etiology, pathology, radiography* Diagnosis, Differential Fluorodeoxyglucose F18 / diagnostic use, pharmacokinetics Humans Lymphoma, Non-Hodgkin / complications*, pathology, radiography Middle Aged Positron-Emission Tomography / standards* Recurrence Tomography, X-Ray Computed / standards* |
| Chemical | |
Reg. No./Substance:
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63503-12-8/Fluorodeoxyglucose F18 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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