| PET: Is myocardial flow quantification a clinical reality? | |
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MedLine Citation:
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PMID: 22733534 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Positron emission tomography (PET) enables quantitative measurements of myocardial blood flow (MBF) and myocardial flow reserve (MFR). Recent developments and improved availability of PET technology have resulted in growing interest in translation of quantitative flow analysis from mainly a research tool to routine clinical practice. Quantitative PET measurements of absolute MBF and MFR have potential to improve accuracy of myocardial perfusion imaging in diagnosis of multivessel coronary artery disease as well as definition of the extent and functional importance of stenoses. This article reviews recent advances and experience in the quantitative myocardial perfusion imaging together with issues that need to be resolved for quantitative analysis to become clinical reality. |
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Authors:
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Antti Saraste; Sami Kajander; Chunlei Han; Sergey V Nesterov; Juhani Knuuti |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology Volume: 19 ISSN: 1532-6551 ISO Abbreviation: J Nucl Cardiol Publication Date: 2012 Oct |
Date Detail:
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Created Date: 2012-10-11 Completed Date: 2012-12-27 Revised Date: 2013-01-17 |
Medline Journal Info:
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Nlm Unique ID: 9423534 Medline TA: J Nucl Cardiol Country: United States |
Other Details:
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Languages: eng Pagination: 1044-59 Citation Subset: IM |
Affiliation:
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Turku PET Centre, University of Turku, Kiinamyllynkatu 4-8, 20520 Turku, Finland. antti.saraste@utu.fi |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Coronary Artery Disease
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radionuclide imaging Coronary Circulation* Data Interpretation, Statistical Humans Myocardial Perfusion Imaging / methods* Positron-Emission Tomography / methods* Rubidium Radioisotopes / diagnostic use |
| Chemical | |
Reg. No./Substance:
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0/Rubidium Radioisotopes |
| Comments/Corrections | |
Comment In:
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J Nucl Cardiol. 2012 Oct;19(5):877-8
[PMID:
22932819
]
J Nucl Cardiol. 2012 Dec;19(6):1243-4; author reply 1245 [PMID: 23070710 ] |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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