Document Detail

PET: Is myocardial flow quantification a clinical reality?
MedLine Citation:
PMID:  22733534     Owner:  NLM     Status:  MEDLINE    
Positron emission tomography (PET) enables quantitative measurements of myocardial blood flow (MBF) and myocardial flow reserve (MFR). Recent developments and improved availability of PET technology have resulted in growing interest in translation of quantitative flow analysis from mainly a research tool to routine clinical practice. Quantitative PET measurements of absolute MBF and MFR have potential to improve accuracy of myocardial perfusion imaging in diagnosis of multivessel coronary artery disease as well as definition of the extent and functional importance of stenoses. This article reviews recent advances and experience in the quantitative myocardial perfusion imaging together with issues that need to be resolved for quantitative analysis to become clinical reality.
Antti Saraste; Sami Kajander; Chunlei Han; Sergey V Nesterov; Juhani Knuuti
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology     Volume:  19     ISSN:  1532-6551     ISO Abbreviation:  J Nucl Cardiol     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-11     Completed Date:  2012-12-27     Revised Date:  2013-01-17    
Medline Journal Info:
Nlm Unique ID:  9423534     Medline TA:  J Nucl Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1044-59     Citation Subset:  IM    
Turku PET Centre, University of Turku, Kiinamyllynkatu 4-8, 20520 Turku, Finland.
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MeSH Terms
Coronary Artery Disease / radionuclide imaging
Coronary Circulation*
Data Interpretation, Statistical
Myocardial Perfusion Imaging / methods*
Positron-Emission Tomography / methods*
Rubidium Radioisotopes / diagnostic use
Reg. No./Substance:
0/Rubidium Radioisotopes
Comment In:
J Nucl Cardiol. 2012 Oct;19(5):877-8   [PMID:  22932819 ]
J Nucl Cardiol. 2012 Dec;19(6):1243-4; author reply 1245   [PMID:  23070710 ]

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