| PET-CT scan is a valuable modality in the diagnosis of fibrolamellar hepatocellular carcinoma: a case report and a summary of recent literature. | |
| | |
MedLine Citation:
|
PMID: 21493692 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
We report a case of liver cancer with features consistent with fibrolamellar hepatocellular carcinoma (FLHCC) detected by PET-CT scan. A 20-year-old female with a large liver tumor was diagnosed with 'malignant hepatic tumor' 2 years earlier and received five courses of transhepatic arterial chemoembolization (TACE) before she presented to our hospital with abdominal distension and mild pain at the right upper quadrant. Ultrasound and CT scan showed a large tumor in the right lobe of the liver. Contrast CT scan and (18)F-FDG PET-CT showed metastatic lesions in multiple organs. The imaging diagnosis was confirmed by an ultrasound-guided fine needle biopsy of the hepatic lesion which showed features of FLHCC. Immunohistochemical staining showed a marked increase in the expressions of Hepar, CD99, MIB1, proliferating cell nuclear antigen (PCNA), Fibronectin, E-cadherin and CK7. The recent knowledge on the FLHCC and the possible applications of PET-CT were discussed. |
| | |
Authors:
|
S Liu; K Wah Chan; J Tong; Y Wang; B Wang; L Qiao |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-4-14 |
Journal Detail:
|
Title: QJM : monthly journal of the Association of Physicians Volume: - ISSN: 1460-2393 ISO Abbreviation: - Publication Date: 2011 Apr |
Date Detail:
|
Created Date: 2011-4-15 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9438285 Medline TA: QJM Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
From the Department of Cadres, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning Province, 110001, China, Department of Pathology, The University of Hong Kong, Hong Kong, Department of Gastroenterology, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning Province, 110001, China and Storr Liver Unit at Westmead Millennium Institute, The University of Sydney at Westmead Hospital, Westmead, NSW 2145, Australia. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Cdt1 proteolysis is promoted by dual PIP degrons and is modulated by PCNA ubiquitylation.
Next Document: Intravenous administration of auto serum-expanded autologous mesenchymal stem cells in stroke.