Document Detail


PET-CT in recurrent head neck cancers: a study to evaluate impact on patient management.
MedLine Citation:
PMID:  19235784     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND AND OBJECTIVES: PET-CT has shown promise in the management of head neck cancers. However, there have been only few studies evaluating its impact on management of patients with recurrent cancers in the presence of available clinicoradiologic methods of assessment. We conducted this study to assess the same in patients with suspected recurrent head and neck cancer. METHODS: Case histories were presented to two oncologists, who were blinded to PET-CT reports. Treatment plans were made by these oncologists based on clinical findings and other conventional imaging. These plans were then compared to the actual treatment received by patients after PET-CT. Any change was recorded as "change in management." RESULTS: Forty-nine patients with suspected recurrent head and neck cancer were evaluated in the study. Overall, there was a 38.7% change in management because of the addition of PET-CT to conventional methods of assessment. Eight patients (16.3%) had a major change in therapy while in 11 patients (22.4%), diagnostic procedures like endoscopies, biopsies and examination under anesthesia were avoided. CONCLUSION: In our study, PET-CT had a significant impact on the management of patients with suspected recurrent head neck cancer.
Authors:
G H Pantvaidya; J P Agarwal; M S Deshpande; V Rangarajan; V Singh; A Kakade; A K D'Cruz
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of surgical oncology     Volume:  100     ISSN:  1096-9098     ISO Abbreviation:  J Surg Oncol     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-09-22     Completed Date:  2009-10-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0222643     Medline TA:  J Surg Oncol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  401-3     Citation Subset:  IM    
Copyright Information:
(c) 2009 Wiley-Liss, Inc.
Affiliation:
Department of Head and Neck Surgery, Tata Memorial Hospital, Mumbai, India.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Aged, 80 and over
Antineoplastic Agents / therapeutic use
Decision Making*
False Negative Reactions
False Positive Reactions
Female
Head and Neck Neoplasms / pathology*,  therapy
Humans
Lymphatic Metastasis / diagnosis
Male
Middle Aged
Neck Dissection
Neoplasm Recurrence, Local / pathology*,  therapy
Palliative Care
Positron-Emission Tomography*
Sensitivity and Specificity
Tomography, X-Ray Computed*
Young Adult
Chemical
Reg. No./Substance:
0/Antineoplastic Agents

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