| PET-CT in radiation oncology: the impact on diagnosis, treatment planning, and assessment of treatment response. | |
| | |
MedLine Citation:
|
PMID: 18845994 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: To review the role of hybrid positron emission tomography (PET)-computed tomography (CT) systems in the design and management of cancer patients in the modern radiation oncology practice. PET is co-registered with CT and incorporated into a systematic approach to the staging, management, and assessment of response and surveillance of a variety of oncologic diagnoses. METHODS: A review of the literature of functional imaging such as PET-CT in staging, treatment plan design, assessment of response and detection of recurrence for tumors involving the head and neck, lung, esophagus, rectum amongst others. RESULTS: PET and PET-CT offer significant advantages which include more accurate staging which often results in management changes in roughly one-third of patients across a number of disease site. More accurate target definition may augment highly conformal radiation treatment plans using intensity-modulated radiation therapy and stereotactic radiosurgery and radiotherapy. CONCLUSION: The emerging data appears to suggest the functional imaging may be a more useful tool to evaluate the therapeutic effect of treatment, detect early failures and prognosticate long-term outcome. |
| | |
Authors:
|
Dwight E Heron; Regiane S Andrade; Sushil Beriwal; Ryan P Smith |
Related Documents
:
|
18177454 - Clinical role of 18f-fdg pet-ct in suspected and potentially operable cholangiocarcinom... 16086544 - Pet in lung cancer. 11202454 - 18f-dopa positron emission tomography for tumour detection in patients with medullary t... 16251394 - T staging of gastric cancer: role of multi-detector row ct. 18375274 - Confocal arthroscopic assessment of osteoarthritis in situ. 21493104 - Accuracy of measurement of hill-sachs lesions with computed tomography. |
Publication Detail:
|
Type: Journal Article; Review |
Journal Detail:
|
Title: American journal of clinical oncology Volume: 31 ISSN: 1537-453X ISO Abbreviation: Am. J. Clin. Oncol. Publication Date: 2008 Aug |
Date Detail:
|
Created Date: 2008-10-10 Completed Date: 2008-11-06 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8207754 Medline TA: Am J Clin Oncol Country: United States |
Other Details:
|
Languages: eng Pagination: 352-62 Citation Subset: IM |
Affiliation:
|
University of Pittsburgh Cancer Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. herond2@upmc.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Clinical Trials as Topic Humans Neoplasms / radionuclide imaging*, radiotherapy* Patient Care Planning Positron-Emission Tomography / methods* Radiation Oncology* Radiopharmaceuticals / diagnostic use* Radiotherapy Planning, Computer-Assisted Tomography, X-Ray Computed / methods* |
| Chemical | |
Reg. No./Substance:
|
0/Radiopharmaceuticals |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The radiation exposure from portal images during the course of breast radiotherapy.
Next Document: Use of the monoclonal antibody anti-HER2 trastuzumab in the treatment of metastatic breast cancer: a...