| PEST regions, proteolysis and cell cycle progression. | |
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MedLine Citation:
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PMID: 2561544 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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How eucaryotic cells control cell division is both a major intellectual challenge and a problem of considerable medical importance. A decade of studies on oncogenes has made it abundantly clear that protein kinases play a central role in regulating mitosis. In this essay, I review a number of recent discoveries providing evidence that selective proteolysis, like phosphorylation, is an important mechanism for ordering metabolic events within the cell cycle. |
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Authors:
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M Rechsteiner |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Revisiones sobre biología celular : RBC Volume: 20 ISSN: 0213-7119 ISO Abbreviation: Revis. Biol. Celular Publication Date: 1989 |
Date Detail:
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Created Date: 1990-07-11 Completed Date: 1990-07-11 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 8712458 Medline TA: Revis Biol Celular Country: SPAIN |
Other Details:
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Languages: eng Pagination: 235-53 Citation Subset: IM |
Affiliation:
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Department of Biochemistry, University of Utah School of Medicine, Salt Lake City 84132. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adenosine Triphosphate
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metabolism Amino Acid Sequence Animals Cell Cycle* Humans Metaphase Molecular Sequence Data Peptide Hydrolases / physiology* Proteins / metabolism* Structure-Activity Relationship Ubiquitins / metabolism* |
| Chemical | |
Reg. No./Substance:
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0/Proteins; 0/Ubiquitins; 56-65-5/Adenosine Triphosphate; EC 3.4.-/Peptide Hydrolases |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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