Document Detail


PEGylated WS2 Nanosheets as a Multifunctional Theranostic Agent for in vivo Dual-Modal CT/Photoacoustic Imaging Guided Photothermal Therapy.
MedLine Citation:
PMID:  24375758     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
A new generation of photothermal theranostic agent is developed based on PEGylated WS2 nanosheets. Bimodal in vivo CT/photoacoustic imaging reveals strong tumor contrast after either intratumoral or intravenous injection of WS2 -PEG. In vivo photothermal treatment is then conducted in a mouse tumor model, achieving excellent therapeutic efficacy with complete ablation of tumors. This work promises further explorations of transition-metal dichalcogenides for biomedical applications, such as cancer imaging and therapy.
Authors:
Liang Cheng; Jingjing Liu; Xing Gu; Hua Gong; Xiaoze Shi; Teng Liu; Chao Wang; Xiaoyong Wang; Gang Liu; Huaiyong Xing; Wenbo Bu; Baoquan Sun; Zhuang Liu
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-12-23
Journal Detail:
Title:  Advanced materials (Deerfield Beach, Fla.)     Volume:  -     ISSN:  1521-4095     ISO Abbreviation:  Adv. Mater. Weinheim     Publication Date:  2013 Dec 
Date Detail:
Created Date:  2013-12-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9885358     Medline TA:  Adv Mater     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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