Document Detail


PCR identification of bacteria in blood culture does not fit the daily workflow of a routine microbiology laboratory.
MedLine Citation:
PMID:  22170900     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We have evaluated the GenoType blood culture assay (Hain Lifescience, Nehren, Germany) for the identification of bacteria in 233 positive blood cultures and assessed its suitability in the workflow of a routine microbiology laboratory. In 68/233 (29.2%) samples, the culture result could not be confirmed by the GenoType assay due to a lack of primers in the test, multiple organisms in the sample, or inconsistency with respect to the identification by culture. Although the GenoType blood culture assay gives satisfactory results for bacteria for which primers are available, there are difficulties in applying the test in the routine microbiology laboratory.
Authors:
Santra Karumaa; Pauliina Kärpänoja; Hannu Sarkkinen
Publication Detail:
Type:  Comparative Study; Evaluation Studies; Journal Article     Date:  2011-12-14
Journal Detail:
Title:  Journal of clinical microbiology     Volume:  50     ISSN:  1098-660X     ISO Abbreviation:  J. Clin. Microbiol.     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-02-20     Completed Date:  2012-05-04     Revised Date:  2012-09-27    
Medline Journal Info:
Nlm Unique ID:  7505564     Medline TA:  J Clin Microbiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1031-3     Citation Subset:  IM    
Affiliation:
Päijät-Häme Social and Health Care Group, Clinical Microbiology, Lahti, Finland.
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MeSH Terms
Descriptor/Qualifier:
Bacteremia / diagnosis*,  microbiology
Bacteria / classification,  genetics,  isolation & purification*
Bacteriological Techniques / methods*
Blood / microbiology*
DNA Primers / genetics
Germany
Humans
Molecular Diagnostic Techniques / methods*
Polymerase Chain Reaction / methods*
Sensitivity and Specificity
Workflow*
Chemical
Reg. No./Substance:
0/DNA Primers
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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