| A PCR-RFLP typing method for adhesion molecule gene polymorphisms and allele frequencies in a normal UK population. | |
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MedLine Citation:
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PMID: 11918635 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We report simple and reproducible PCR-RFLP typing methods for the polymorphisms in the ICAM-1, E-selectin and PECAM-1 genes. The genotype and allele frequencies detected in a normal UK population did not deviate significantly from the Hardy-Weinberg equilibrium; neither did they differ from frequencies previously reported using SSP or SSCP methods. |
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Authors:
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R A Gbadegesin; C J Watson; S A Cotton; P E C Brenchley; N J A Webb |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics Volume: 29 ISSN: 0960-7420 ISO Abbreviation: Eur. J. Immunogenet. Publication Date: 2002 Apr |
Date Detail:
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Created Date: 2002-03-28 Completed Date: 2002-08-08 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 9106962 Medline TA: Eur J Immunogenet Country: England |
Other Details:
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Languages: eng Pagination: 109-11 Citation Subset: IM |
Affiliation:
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Department of Nephrology, Royal Manchester Children's Hospital, Pendlebury, Manchester M27 4HA, UK. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Alleles Antigens, CD31 / genetics* E-Selectin / genetics* Gene Frequency Great Britain Humans Intercellular Adhesion Molecule-1 / genetics* Polymerase Chain Reaction / methods* Polymorphism, Genetic Polymorphism, Restriction Fragment Length* |
| Chemical | |
Reg. No./Substance:
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0/Antigens, CD31; 0/E-Selectin; 126547-89-5/Intercellular Adhesion Molecule-1 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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