Document Detail

PBDE exposure from food in Ireland: optimising data exploitation in probabilistic exposure modelling.
MedLine Citation:
PMID:  20664651     Owner:  NLM     Status:  MEDLINE    
Polybrominated diphenyl ethers (PBDEs) are a class of brominated flame retardants added to plastics, polyurethane foam, electronics, textiles, and other products. These products release PBDEs into the indoor and outdoor environment, thus causing human exposure through food and dust. This study models PBDE dose distributions from ingestion of food for Irish adults on congener basis by using two probabilistic and one semi-deterministic method. One of the probabilistic methods was newly developed and is based on summary statistics of food consumption combined with a model generating realistic daily energy supply from food. Median (intermediate) doses of total PBDEs are in the range of 0.4-0.6 ng/kg(bw)/day for Irish adults. The 97.5th percentiles of total PBDE doses lie in a range of 1.7-2.2 ng/kg(bw)/day, which is comparable to doses derived for Belgian and Dutch adults. BDE-47 and BDE-99 were identified as the congeners contributing most to estimated intakes, accounting for more than half of the total doses. The most influential food groups contributing to this intake are lean fish and salmon which together account for about 22-25% of the total doses.
David Trudel; Christina Tlustos; Natalie Von Goetz; Martin Scheringer; Konrad Hungerbühler
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-07-28
Journal Detail:
Title:  Journal of exposure science & environmental epidemiology     Volume:  21     ISSN:  1559-064X     ISO Abbreviation:  J Expo Sci Environ Epidemiol     Publication Date:    2011 Nov-Dec
Date Detail:
Created Date:  2011-10-20     Completed Date:  2012-02-15     Revised Date:  2012-03-26    
Medline Journal Info:
Nlm Unique ID:  101262796     Medline TA:  J Expo Sci Environ Epidemiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  565-75     Citation Subset:  IM    
Institute for Chemical and Bioengineering, ETH Zurich, Zurich, Switzerland.
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MeSH Terms
Body Burden
Environmental Exposure / analysis*,  statistics & numerical data
Flame Retardants / analysis*
Food Contamination / analysis*
Halogenated Diphenyl Ethers / analysis*
Models, Biological
Models, Statistical*
Risk Assessment / methods,  statistics & numerical data
Time Factors
Reg. No./Substance:
0/Flame Retardants; 0/Halogenated Diphenyl Ethers; 32534-81-9/pentabromodiphenyl ether

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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