| The PABA story. | |
| | |
MedLine Citation:
|
PMID: 10098293 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The qualities of para-aminobenzoic acid (PABA) are discussed and an account is given of how it came to be the favourite sunscreen of the post World War II era. Slowly, however, dermatologists became aware that it was a fairly common sensitizer and that it tended to cross-sensitize with compounds of similar chemical structure both in contact with the skin and given as systemic drugs. Furthermore, continued exposure to chemicals of this type could lead to autoimmune responses especially systemic lupus erythematosus and dermatomyositis. Discussion of these complications from the use of PABA took place at two meetings of the Dermatological Association of Australia in 1964 and 1965, and played a part in the slow withdrawal of PABA from sunscreens. |
| | |
Authors:
|
B S Mackie; L E Mackie |
Related Documents
:
|
3328473 - Pavlovian orienting reflex. 15260533 - The permanent dipole moment of gas-phase para-amino benzoic acid revisited. 17613033 - Preparation and evaluation of mucin-gelatin mucoadhesive microspheres for rectal delive... |
Publication Detail:
|
Type: Historical Article; Journal Article |
Journal Detail:
|
Title: The Australasian journal of dermatology Volume: 40 ISSN: 0004-8380 ISO Abbreviation: Australas. J. Dermatol. Publication Date: 1999 Feb |
Date Detail:
|
Created Date: 1999-04-20 Completed Date: 1999-04-20 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 0135232 Medline TA: Australas J Dermatol Country: AUSTRALIA |
Other Details:
|
Languages: eng Pagination: 51-3 Citation Subset: IM; Q |
Affiliation:
|
Prince Henry Hospital, Sydney, Australia. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
4-Aminobenzoic Acid
/
adverse effects,
history* Australia Drug Eruptions / etiology, history History, 20th Century Humans Sunscreening Agents / adverse effects, history* |
| Chemical | |
Reg. No./Substance:
|
0/Sunscreening Agents; 150-13-0/4-Aminobenzoic Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Band-like sebaceous hyperplasia over the penis.
Next Document: ENT malignancies. What the GP needs to know.