Document Detail

P300 in Behcet's patients without neurological manifestations.
MedLine Citation:
PMID:  11252299     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Behcet's disease is the association of recurrent aphthous stomatitis with genital ulceration and eye disease. Neurologic involvement patterns include meningomyelitis, a brain stem syndrome, pyramidal and extrapyramidal abnormality and stroke. In the present study, subclinical involvement was investigated by using P300 in Behcet's patients without neurological manifestation. METHODS: Fifteen patients and 15 healthy volunteers were accepted for the study. P300 from vertex (Cz) electrode sites of the 10-20 system using electrodes and motor response time were recorded. RESULTS: Patients had significantly prolonged latencies of P300 as compared to normal controls (p=0.013) but no significant differences in amplitude (p=1.000). Patients showed a significantly delayed motor response time than controls (p=0.006). Nine patients (60%) had P300 latency and eight patients (53.3%) had motor response time values exceeding the mean of controls by two standard deviations. CONCLUSION: The findings suggest that the P300 measures and motor response time may reflect subclinical neurologic involvement in Behcet's disease.
H Kececi; M Akyol
Related Documents :
9474059 - Motor and somatosensory evoked potentials in cervical spondylotic myelopathy.
9277029 - Pattern-reversal visual evoked potentials in migraineurs with or without visual aura.
3267489 - Abnormalities of visual evoked responses in hyperprolactinaemia.
8930419 - Evoked potential studies in thalamic hemorrhage.
21229279 - Twelve potential fibrosis markers to differentiate mild liver fibrosis from cirrhosis i...
8884539 - Central and peripheral neural responses in males with idiopathic hypogonadotropic hypog...
15598979 - Intratumoral injection of dendritic cells engineered to secrete interleukin-12 by recom...
6781399 - Measurement of optokinetic nystagmus for otoneurological diagnosis.
24261759 - Early diagnosis and treatment of steroid-induced diabetes mellitus in patients with rhe...
Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques     Volume:  28     ISSN:  0317-1671     ISO Abbreviation:  Can J Neurol Sci     Publication Date:  2001 Feb 
Date Detail:
Created Date:  2001-03-16     Completed Date:  2001-06-21     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0415227     Medline TA:  Can J Neurol Sci     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  66-9     Citation Subset:  IM    
Department of Neurology, Medical Faculty of Cumhuriyet University, Sivas, Turkey.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Behcet Syndrome / physiopathology*
Event-Related Potentials, P300 / physiology*
Evoked Potentials, Auditory, Brain Stem / physiology
Evoked Potentials, Motor / physiology
Middle Aged

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Treatment costs for glioblastoma multiforme in Nova Scotia.
Next Document:  Gait analysis in advanced Parkinson's disease--effect of levodopa and tolcapone.