Document Detail

P300 and CT scan in patients with chronic schizophrenia.
MedLine Citation:
PMID:  3447666     Owner:  NLM     Status:  MEDLINE    
Twenty chronic male schizophrenic subjects aged 30-50 years were examined by an auditory event-related potential procedure for the evaluation of the P300 component, a CT scan and a neuropsychological test battery. The P300 latency was increased and its amplitude was reduced. CT scan measures showed lateral and third ventricle enlargement, and there was a global neuropsychological impairment. Poor neuropsychological performances were consistently associated with delayed P300 latencies, but not with CT scan measures. Ventricular enlargement was more pronounced among subjects with a negative family history for major psychiatric disorders.
A Romani; S Merello; L Gozzoli; F Zerbi; M Grassi; V Cosi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The British journal of psychiatry : the journal of mental science     Volume:  151     ISSN:  0007-1250     ISO Abbreviation:  Br J Psychiatry     Publication Date:  1987 Oct 
Date Detail:
Created Date:  1988-05-27     Completed Date:  1988-05-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0342367     Medline TA:  Br J Psychiatry     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  506-13     Citation Subset:  IM    
C. Mondino Institute, Neurological Clinic, Pavia, Italy.
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MeSH Terms
Brain / radiography*
Evoked Potentials, Auditory*
Middle Aged
Neuropsychological Tests
Schizophrenia / diagnosis*,  physiopathology
Schizophrenic Psychology
Tomography, X-Ray Computed

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