Document Detail


P2Y12 Antagonists in Acute Coronary Syndrome: In Whom Should They Be Started, and When?
MedLine Citation:
PMID:  21487719     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Acute coronary syndromes reflect a spectrum of disease related, most commonly, to the sudden reduction in blood flow to a portion of myocardium. The underlying pathogenesis of the reduction in coronary flow is related to the sudden rupture of an atherosclerotic plaque, with subsequent thrombus formation leading to either vascular occlusion or microembolization. Clinicians combat this process with antithrombotic therapy, which typically includes both anticoagulant and antiplatelet therapy, and mechanical therapies, such as percutaneous coronary interventions, nearly always using stents. This review focuses on P2Y12 antagonists as one component of our armamentarium of antiplatelet therapies, specifically on data addressing in whom, when, which agent, and in what dose such agents should be administered.
Authors:
Christopher W Good; Peter B Berger
Related Documents :
2882869 - A pathophysiologic basis for the clinical classification and management of unstable ang...
21401459 - A new algorithm for the management of stable coronary artery disease incorporating ct c...
6888439 - Unstable angina and progression of coronary atherosclerosis.
1083279 - Prognostic significance of endocardial viability ratio in aortocoronary bypass surgery.
21532179 - Noninvasive assessment of coronary plaque using multidetector row computed tomography: ...
10329069 - The impact of an end-point committee in a large multicentre, randomized, placebo-contro...
16369379 - Thyrotoxic atrial fibrillation.
17102829 - Transfer for urgent percutaneous coronary intervention early after thrombolysis for st-...
14975699 - Evidence for a protective role played by the na+/ca2+ exchanger in cerebral ischemia in...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-4-13
Journal Detail:
Title:  Current cardiology reports     Volume:  -     ISSN:  1534-3170     ISO Abbreviation:  -     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-4-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100888969     Medline TA:  Curr Cardiol Rep     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Geisinger Center for Clinical Studies, 100 North Academy Avenue, MC 40-04, Danville, PA, 17822, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  The effect of different etiologies of hepatic impairment on the pharmacokinetics of gefitinib.
Next Document:  Understanding the connection between spiritual well-being and physical health: an examination of amb...